Professor at China University of Mining and Technology, China
Dr. Li Ji, a renowned researcher in environmental chemistry, is currently serving as a Professor and Dean at the Department of Environmental Science, School of Environment Science and Spatial Informatics, China University of Mining and Technology. With a rich academic background and extensive professional experience, Dr. Ji has contributed significantly to the understanding of biotransformation mechanisms of xenobiotics and the development of structure-activity relationships for predicting the toxicological effects of chemicals. His expertise lies in combining computational simulations with experimental approaches to unravel complex environmental processes. Dr. Ji has received numerous awards and grants for his outstanding contributions to the field.
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Scopus Profile
Dr. Li Ji has an impressive publication record, with numerous high-impact research articles in esteemed journals such as Environment International, Environmental Science & Technology, and Chemical Research in Toxicology. His work has garnered significant attention in the scientific community, as evidenced by his citation metrics and collaborations with leading researchers worldwide. Dr. Ji’s publications reflect his expertise in computational chemistry, biotransformation mechanisms, and predictive modeling in environmental toxicology.
- Citations: The individual has received a total of 599 citations from 440 documents, indicating the impact and reach of their research.
- Documents: They have authored or co-authored 25 documents indexed in Scopus.
- h-index: The h-index is a metric used to measure the productivity and citation impact of a researcher’s publications. With an h-index of 16, this individual has 16 papers that have each received at least 16 citations.
Education
Dr. Li Ji obtained his Dr.rer.nat. in Environmental Chemistry from the Helmholtz Centre for Environmental Research, Germany, in 2012. Prior to that, he completed his M.S.Eng. in Environmental Chemistry at Nanjing University, China, in 2008, and his B.Sc.Eng. in Environmental Engineering at Yangzhou University, China, in 2005. His academic journey provided him with a strong foundation in environmental science and equipped him with the necessary skills to conduct cutting-edge research in his field.
Research Focus
Dr. Ji’s research focuses on elucidating the biotransformation mechanisms of xenobiotics catalyzed by enzymes in various organisms, including humans, animals, plants, and microorganisms. He employs a multidisciplinary approach, combining computational simulations with experimental techniques, to investigate kinetic isotope effects, build structure-activity relationships, and develop predictive models for assessing the toxicological effects of chemicals. His work contributes to a deeper understanding of environmental processes and aids in the development of strategies for pollution mitigation and risk assessment.
Professional Journey
Throughout his career, Dr. Li Ji has held various academic and research positions at esteemed institutions worldwide. He has served as a Professor, Dean, Senior Principal Investigator, and Lecturer at institutions such as China University of Mining and Technology, Zhejiang University, Kyoto University, and Lodz University of Technology. His diverse professional journey has provided him with unique perspectives and opportunities to collaborate with experts from different backgrounds, enriching his research endeavors and academic contributions.
Honors & Awards
Dr. Ji’s exceptional research contributions have been recognized through prestigious honors and awards. Notably, he was awarded the FY2019 JSPS Invitational Fellowships for Research in Japan, acknowledging his outstanding achievements in environmental chemistry. Additionally, Dr. Ji has received external funding from renowned organizations such as the National Natural Science Foundation of China and The Japan Society for the Promotion of Science, further affirming the significance of his research in the scientific community.
Publications Noted & Contributions
Dr. Ji has made notable contributions to the scientific literature through his extensive publication record. His research articles in reputable journals have shed light on various aspects of environmental chemistry, including the metabolic mechanisms of emerging pollutants, kinetic isotope effects in biodegradation mechanisms, and the development of predictive models for assessing chemical toxicity. These publications represent Dr. Ji’s dedication to advancing knowledge in his field and have significantly influenced environmental science research worldwide.
Insight into Chemically Reactive Metabolites of Aliphatic Amine Pollutants: A De Novo Prediction Strategy and Case Study of Sertraline
- Journal: Environment International
- Date: 2024-04
- DOI: 10.1016/j.envint.2024.108636
- Contributors: Lingmin Jin; Shiyang Cheng; Wen Ding; Jingru Huang; Rudi van Eldik; Li Ji
- Summary: This article presents a de novo prediction strategy to gain insight into the chemically reactive metabolites of aliphatic amine pollutants, using sertraline as a case study. By combining computational simulations with experimental validation, the study offers valuable insights into the metabolic pathways and potential risks associated with aliphatic amine pollutants, contributing to the understanding of environmental chemistry.
Emerging Metabolic Profiles of Sulfonamide Antibiotics by Cytochromes P450: A Computational–Experimental Synergy Study on Emerging Pollutants
- Journal: Environmental Science & Technology
- Date: 2023-04-04
- DOI: 10.1021/acs.est.3c00071
- Contributors: Huanni Zhang; Xiaoqing Wang; Runqian Song; Wen Ding; Fei Li; Li Ji
- Summary: This article investigates the emerging metabolic profiles of sulfonamide antibiotics by cytochromes P450, employing a computational-experimental synergy approach. By integrating computational simulations with experimental data, the study provides valuable insights into the biotransformation mechanisms of sulfonamide antibiotics, contributing to the understanding of their environmental fate and potential ecological impacts.
Theoretical Kinetic Isotope Effects in Establishing the Precise Biodegradation Mechanisms of Organic Pollutants
- Journal: Environmental Science & Technology
- Date: 2023-03-28
- DOI: 10.1021/acs.est.2c04755
- Contributors: Li Ji; Huanni Zhang; Wen Ding; Runqian Song; Ye Han; Haiying Yu; Piotr Paneth
- Summary: This article explores the theoretical kinetic isotope effects in establishing the precise biodegradation mechanisms of organic pollutants. By employing computational simulations, the study elucidates the role of isotopic labeling in understanding biodegradation pathways, offering insights into environmental processes and facilitating the development of effective pollution mitigation strategies.
Using Physical Organic Chemistry Knowledge to Predict Unusual Metabolites of Synthetic Phenolic Antioxidants by Cytochrome P450
- Journal: Chemical Research in Toxicology
- Date: 2022-05-16
- DOI: 10.1021/acs.chemrestox.2c00021
- Contributors: Huanni Zhang; Runqian Song; Fangjie Guo; Lihong Chai; Wuwei Wang; Jingyi Zeng; Haiying Yu; Li Ji
- Summary: This article employs physical organic chemistry knowledge to predict unusual metabolites of synthetic phenolic antioxidants by cytochrome P450. By integrating computational modeling with experimental validation, the study provides insights into the biotransformation pathways of synthetic phenolic antioxidants, enhancing our understanding of their environmental behavior and potential toxicological effects.
Computational Investigation of the Bisphenolic Drug Metabolism by Cytochrome P450: What Factors Favor Intramolecular Phenol Coupling
- Journal: Chemical Research in Toxicology
- Date: 2022-03-21
- DOI: 10.1021/acs.chemrestox.1c00350
- Contributors: Lihong Chai; Huanni Zhang; Fangjie Guo; Runqian Song; Haiying Yu; Li Ji
- Summary: This article presents a computational investigation of the bisphenolic drug metabolism by cytochrome P450, focusing on factors favoring intramolecular phenol coupling. By elucidating the underlying mechanisms through computational simulations, the study enhances our understanding of the metabolic pathways of bisphenolic drugs, providing valuable insights for pharmacological and environmental research.
Research Timeline
Dr. Li Ji’s research timeline illustrates a progressive trajectory marked by significant achievements and milestones. From his academic pursuits to his professional appointments and research endeavors, each phase of his career has contributed to his growth as a leading expert in environmental chemistry. His timeline reflects a continuous commitment to excellence, innovation, and collaboration, shaping his journey as a prominent figure in the field of environmental science.
Collaborations and Projects
Dr. Ji’s collaborations and projects encompass a wide range of international partnerships and research initiatives aimed at addressing critical environmental challenges. Collaborating with esteemed researchers such as Prof. Dr. Rudi van Eldik, Prof. Dr. Piotr Paneth, and Dr. Sam P. de Visser, Dr. Ji has contributed to groundbreaking studies on biotransformation mechanisms, isotope effects, and predictive modeling in environmental chemistry. His involvement in various projects funded by prestigious organizations underscores the significance of his research in tackling global environmental issues.
