70 / 100

Assoc. Prof. Dr. Guoping Zheng | Medicine and Dentistry | Best Researcher Award

Laboratory head at University of Sydney (WIMR), Australia

Associate Professor Guoping Zheng is a renowned researcher and academic in the field of medicine, specializing in kidney injury, repair, and fibrosis. He is currently an Associate Professor at the University of Sydney, within the Faculty of Medicine and Health, and holds a prestigious NHMRC Principal Research Fellowship at the Westmead Institute for Medical Research. Dr. Zheng has led pioneering research projects in kidney transplantation, fibrosis, and inflammatory diseases, contributing significantly to our understanding of kidney pathophysiology and potential therapeutic interventions. With a research portfolio that spans over two decades, Dr. Zheng has garnered international recognition for his innovative work in renal medicine, including developing engineered macrophages for treating chronic kidney disease. His research impact is further demonstrated by his high citation index, editorial roles in top journals, and his numerous academic and institutional leadership positions.

Professional Profile

Education

Dr. Guoping Zheng has an impressive educational background in medical and molecular sciences. He earned his PhD from the University of Sydney’s Faculty of Medicine, where he conducted research from 1998 to 2002. Before that, he completed a Master of Medicine by research at Shanxi Medical University in China, specializing in biochemistry and molecular biology from 1985 to 1988. Dr. Zheng also holds an MBBS degree from the same institution, completed in 1985. His educational journey laid a strong foundation for his future research and teaching career, enabling him to contribute extensively to the understanding of kidney disease, renal fibrosis, and related inflammatory processes.

Professional Experience

Dr. Zheng has held a distinguished academic career, with extensive roles at the University of Sydney and the Westmead Institute for Medical Research (WIMR). Since 2003, he has been a key figure at the Centre for Transplantation and Renal Research, where he currently serves as an Associate Professor and leads the Kidney Injury Repair and Fibrosis Study Group. His prior roles include Senior Research Officer and Research Officer, with a focus on kidney pathology. Dr. Zheng has also been an NHMRC Peter Doherty Fellow and a lecturer at the University of Sydney. His professional trajectory reflects a deep commitment to advancing medical research and education, particularly in the field of nephrology and renal transplantation. Additionally, Dr. Zheng has held several executive committee positions at WIMR and serves as a mentor and reviewer for multiple research bodies and academic institutions globally.

Research Interests

Dr. Zheng’s research focuses on kidney injury, repair mechanisms, and fibrosis, particularly in the context of chronic kidney disease and renal transplantation. His work aims to uncover novel therapeutic strategies for kidney fibrosis, a key driver of kidney failure. Dr. Zheng has explored several molecular pathways, including the role of macrophages, TGF-β signaling, and matrix metalloproteinases in fibrosis and inflammation. His research also investigates the potential of engineered cells, such as chimeric antigen receptor macrophages, to prevent kidney damage. Another significant area of interest includes the differentiation of pro-fibrotic from anti-inflammatory effects of TGF-β in kidney fibrosis, which may lead to more effective treatments for renal diseases. Dr. Zheng’s interdisciplinary approach bridges biochemistry, molecular biology, and clinical medicine, advancing both basic science and therapeutic innovation in renal health.

Awards and Honors

Dr. Zheng has received numerous awards and honors throughout his distinguished career, recognizing his outstanding contributions to medical research. He has been awarded the prestigious Westmead Millennium Institute Science Prize five times (2006, 2010, 2013, 2017, and 2021), which is granted to the best original research within his institution. Additionally, he was a finalist for the Basic Science Award at both the 55th ANZSN Annual Scientific Meeting (2020) and the 5th Asian Pacific Congress of Nephrology (2016). Dr. Zheng has also received various recognitions for his poster presentations and research symposia, including multiple “Best Poster Presentation Prizes” at the Annual Research Symposium during Hospital Week. These honors reflect his ongoing dedication to advancing scientific understanding in nephrology and transplantation. Moreover, he has been recognized internationally with travel awards and fellowships, including the New Investigator Travel Award for the Pan-Pacific Connective Tissue Societies Symposium in 1999.

Conclusion

Associate Professor Guoping Zheng stands as a highly suitable candidate for the Best Researcher Award. His extensive research experience, influential publications, multiple awards, and leadership in renal medicine demonstrate a strong commitment to advancing medical knowledge and treatment options for kidney disease. Areas of further development, such as advancing his work’s clinical translation and expanding international collaborations, could add even more depth to his already impressive career. Overall, Dr. Zheng’s accomplishments, recognized expertise, and continuous contributions make him a deserving candidate for this prestigious recognition.

Publications Top Noted

  1. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)
    • Authors: DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, …
    • Year: 2021
    • Citations: 10,941
  2. Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes
    • Authors: DJ Klionsky, H Abeliovich, P Agostinis, DK Agrawal, G Aliev, DS Askew, …
    • Year: 2008
    • Citations: 2,962
  3. E‐Cadherin/β‐Catenin Complex and the Epithelial Barrier
    • Authors: X Tian, Z Liu, B Niu, J Zhang, TK Tan, SR Lee, Y Zhao, DCH Harris, …
    • Year: 2011
    • Citations: 610
  4. Ex vivo programmed macrophages ameliorate experimental chronic inflammatory renal disease
    • Authors: Y Wang, YP Wang, G Zheng, VWS Lee, L Ouyang, DHH Chang, …
    • Year: 2007
    • Citations: 449
  5. IL-10/TGF-β–modified macrophages induce regulatory T cells and protect against adriamycin nephrosis
    • Authors: Q Cao, Y Wang, D Zheng, Y Sun, Y Wang, VWS Lee, G Zheng, TK Tan, …
    • Year: 2010
    • Citations: 319
  6. Disruption of E-cadherin by matrix metalloproteinase directly mediates epithelial-mesenchymal transition downstream of transforming growth factor-β1 in renal tubular epithelial …
    • Authors: G Zheng, JG Lyons, TK Tan, Y Wang, TT Hsu, D Min, L Succar, …
    • Year: 2009
    • Citations: 286
  7. Characterization of murine macrophages from bone marrow, spleen and peritoneum
    • Authors: C Wang, X Yu, Q Cao, Y Wang, G Zheng, TK Tan, H Zhao, Y Zhao, …
    • Year: 2013
    • Citations: 273
  8. Discrete functions of M2a and M2c macrophage subsets determine their relative efficacy in treating chronic kidney disease
    • Authors: J Lu, QI Cao, D Zheng, Y Sun, C Wang, X Yu, YA Wang, VWS Lee, …
    • Year: 2013
    • Citations: 254
  9. Macrophage matrix metalloproteinase-9 mediates epithelial-mesenchymal transition in vitro in murine renal tubular cells
    • Authors: TK Tan, G Zheng, TT Hsu, Y Wang, VWS Lee, X Tian, Y Wang, Q Cao, …
    • Year: 2010
    • Citations: 185
  10. Matrix metalloproteinases contribute to kidney fibrosis in chronic kidney diseases
    • Authors: H Zhao, Y Dong, X Tian, TK Tan, Z Liu, Y Zhao, Y Zhang, DCH Harris, …
    • Year: 2013
    • Citations: 177
  11. Matrix metalloproteinase-9 of tubular and macrophage origin contributes to the pathogenesis of renal fibrosis via macrophage recruitment through osteopontin cleavage
    • Authors: T Kui Tan, G Zheng, TT Hsu, S Ra Lee, J Zhang, Y Zhao, X Tian, Y Wang, …
    • Year: 2013
    • Citations: 175
  12. CD4+ CD25+ regulatory T cells protect against injury in an innate murine model of chronic kidney disease
    • Authors: D Mahajan, Y Wang, X Qin, Y Wang, G Zheng, YM Wang, SI Alexander, …
    • Year: 2006
    • Citations: 173
  13. Potentiating tissue-resident type 2 innate lymphoid cells by IL-33 to prevent renal ischemia-reperfusion injury
    • Authors: Q Cao, Y Wang, Z Niu, C Wang, R Wang, Z Zhang, T Chen, XM Wang, …
    • Year: 2018
    • Citations: 114
  14. Renal F4/80+ CD11c+ mononuclear phagocytes display phenotypic and functional characteristics of macrophages in health and in adriamycin nephropathy
    • Authors: Q Cao, Y Wang, XM Wang, J Lu, VWS Lee, Q Ye, H Nguyen, G Zheng, …
    • Year: 2015
    • Citations: 112
  15. Transfused macrophages ameliorate pancreatic and renal injury in murine diabetes mellitus
    • Authors: D Zheng, Y Wang, Q Cao, VWS Lee, G Zheng, Y Sun, TK Tan, Y Wang, …
    • Year: 2011
    • Citations: 100
Guoping Zheng | Medicine and Dentistry | Best Researcher Award

You May Also Like