Ivanka Georgieva Tsacheva is an accomplished molecular immunologist with expertise in protein-protein recognition within innate immunity and the molecular mechanisms of autoimmunity. With an M.Sc. in “Gene and Cellular Engineering” and a Ph.D. in Molecular Biology, she has held positions as Assistant and Associate Professor of Molecular Immunology at Sofia University. Her research interests include investigating the interaction of complement components with various ligands, with a focus on understanding autoimmune diseases like lupus nephritis. Tsacheva’s contributions to the field have been recognized through her participation in prestigious projects funded by the Bulgarian National Science Fund (NSF) and the European scientific community.
Author Metrics:
As a prolific researcher, Tsacheva has accumulated a strong publication record, with her work cited by peers in the field. Her contributions have enhanced the understanding of protein-protein interactions in innate immunity and have implications for the development of targeted therapies for autoimmune disorders.
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Ivanka G. Tsacheva is affiliated with Sofia University St. Kliment Ohridski in Sofia, Bulgaria. With 220 citations across 177 documents and 24 publications to her name, Tsacheva has demonstrated a consistent presence in academic discourse. Her h-index, standing at 6, signifies the impact of her work within her field. Tsacheva’s contributions to research are evident, and her affiliation with Sofia University underscores her commitment to advancing knowledge and scholarship. As a member of the academic community, Tsacheva continues to engage in scholarly pursuits, further enriching her field of study.
Education:
Tsacheva obtained her M.Sc. in “Gene and Cellular Engineering” from Sofia University, followed by a Ph.D. in Molecular Biology. Her doctoral research focused on the analysis of the interaction between the C1q subcomponent of complement and its ligands, both immunoglobulin and nonimmunoglobulin, providing foundational knowledge in molecular immunology.
Research Focus:
Tsacheva’s research primarily revolves around protein-protein recognition in innate immunity and the molecular mechanisms underlying autoimmunity. Her work delves into understanding the interaction of complement proteins with various ligands, shedding light on the pathogenesis of autoimmune diseases such as lupus nephritis.
Professional Journey:
Throughout her career, Tsacheva has progressed from an Assistant Professor to an Associate Professor of Molecular Immunology at Sofia University. She has contributed significantly to the field through her teaching, research, and supervisory roles, advancing our understanding of immune responses and autoimmune disorders.
Honors & Awards:
Tsacheva’s contributions to molecular immunology have been recognized through her involvement in prestigious projects funded by organizations such as the Bulgarian National Science Fund (NSF). Her dedication to research and academic excellence has earned her respect within the scientific community.
Publications Top Noted & Contributions:
Tsacheva has made notable contributions to the scientific literature, with publications in reputable journals such as the European Journal of Immunology and Molecular Biotechnology. Her research findings have provided valuable insights into autoimmune diseases and the role of complement proteins in immune responses.
Title: Galectin-3 – A novel ligand of complement protein C1q
- Journal: International Journal of Biological Macromolecules
- Published Date: February 2024
- DOI: 10.1016/j.ijbiomac.2024.129930
- Contributors: Gabriela Radulova; Alexandra Kapogianni; Ginka Cholakova; Stoyan Iliev; Anela Ivanova; Vanya Bogoeva; Ivanka Tsacheva
Title: Exploring the Phytochemical Composition and Biological Potential of Balkan Endemic Species Stachys scardica Griseb
- Journal: Plants
- Published Date: December 21, 2023
- DOI: 10.3390/plants13010030
- Contributors: Desislava I. Mantovska; Miroslava K. Zhiponova; Detelina Petrova; Kalina Alipieva; Georgi Bonchev; Irina Boycheva; Yana Evstatieva; Dilyana Nikolova; Ivanka Tsacheva; Svetlana Simova et al.
Title: Uncovering the Interrelation between Metabolite Profiles and Bioactivity of In Vitro- and Wild-Grown Catmint (Nepeta nuda L.)
- Journal: Metabolites
- Published Date: October 20, 2023
- DOI: 10.3390/metabo13101099
- Contributors: Anna Zaharieva; Krasimir Rusanov; Mila Rusanova; Momchil Paunov; Zhenya Yordanova; Desislava Mantovska; Ivanka Tsacheva; Detelina Petrova; Kiril Mishev; Petre I. Dobrev et al.
Title: Biological Activity and NMR-Fingerprinting of Balkan Endemic Species Stachys thracica Davidov
- Journal: Metabolites
- Published Date: March 16, 2022
- DOI: 10.3390/metabo12030251
- Contributors: Desislava I. Mantovska; Miroslava K. Zhiponova; Milen I. Georgiev; Kalina Alipieva; Ivanka Tsacheva; Svetlana Simova; Zhenya P. Yordanova
Title: Autoinduction as Means for Optimization of the Heterologous Expression of Recombinant Single-Chain Fv (scFv) Antibodies
- Journal: Molecular Biotechnology
- Published Date: November 2, 2021
- DOI: 10.1007/s12033-021-00363-2
- Contributors: Ginka Nikolova; Yana Georgieva; Alexandra Atanasova; Gabriela Radulova; Alexandra Kapogianni; Ivanka Tsacheva
Research Timeline:
Throughout her career, Tsacheva has embarked on a journey of scientific discovery, starting from her graduate studies to her current role as an Associate Professor. Her research trajectory has been marked by significant milestones, including participation in interdisciplinary projects and the supervision of doctoral students, all aimed at advancing our knowledge of molecular immunology and autoimmune diseases.
