Bio Summary:
Dr. Kailiang Zhou is a distinguished male researcher, attending physician, and associate professor in the field of orthopedics. He holds a Ph.D. in Surgery and is affiliated with the Department of Orthopaedics at the Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University in China. With a comprehensive academic background and a focus on orthopedic trauma, Dr. Zhou has made significant contributions to the field through his research and clinical expertise.
Education:
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Ph.D. in Surgery:
- Wenzhou Medical University (2017-2020)
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Master’s in Surgery:
- Wenzhou Medical University (2013-2016)
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Bachelor’s in Clinical Medicine:
- Wenzhou Medical University (2008-2013)
Research Focus:
Dr. Zhou’s primary research interests lie in the realm of orthopedic trauma, specifically concentrating on the microenvironment and regulations of cell programmed death in spinal cord injuries and wound healing. His current research directions include autophagy and spinal cord injury, pyroptosis and spinal cord injury, and the role of extracellular vesicles (apoptotic bodies) in orthopedic trauma.
Professional Journey:
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Resident:
- Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University (2016.08~2020.12)
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Visiting Fellow:
- University of Maryland School of Medicine (2016.08~2017.08)
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Lecturer:
- Wenzhou Medical University (2020.12~2022.12)
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Attending Physician:
- Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University (2021.01~present)
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Associate Researcher:
- Wenzhou Medical University (2022.01~2022.12)
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Associate Professor:
- Wenzhou Medical University (2023.01~~present)
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Researcher:
- Wenzhou Medical University (2023.01~~present)
Honors & Awards:
- Outstanding Graduate in Zhejiang Province
- Nominated for Excellent Doctoral Dissertation in Zhejiang Province
- Lancet Research Award at the Zhejiang Orthopedics Annual Conference
- Selected as the training object of “New Talent in the Medical Industry” in Zhejiang Province
Publications Top Noted & Contributions:
As the first or corresponding author, Dr. Zhou has published 46 papers in renowned journals such as Signal Transmit Target Ther, Autophagy, Redox Biology, Theranostics, and Br J Pharmacol. His research covers diverse topics, including the enhancement of autophagy, the alleviation of pyroptosis and necroptosis, and the impact of caloric restriction mimetics on spinal cord injuries.
Title: Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)
- Authors: DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, …
- Journal: Autophagy (2021)
- Volume and Issue: 17(1)
- Pages: 1-382
- Citations: 10,206
- Year: 2021
- Contribution: This publication likely serves as a comprehensive guide for researchers in the field of autophagy, providing guidelines for the use and interpretation of assays for monitoring autophagy.
Title: Metformin protects against apoptosis and senescence in nucleus pulposus cells and ameliorates disc degeneration in vivo
- Authors: D Chen, D Xia, Z Pan, D Xu, Y Zhou, Y Wu, N Cai, Q Tang, C Wang, …
- Journal: Cell Death & Disease (2016)
- Volume and Issue: 7(10)
- Pages: e2441-e2441
- Citations: 272
- Year: 2016
- Contribution: This study suggests that metformin has protective effects against apoptosis and senescence in nucleus pulposus cells and may be beneficial in ameliorating disc degeneration in vivo.
Title: Endothelial cell pyroptosis plays an important role in Kawasaki disease via HMGB1/RAGE/cathepsin B signaling pathway and NLRP3 inflammasome activation
- Authors: C Jia, J Zhang, H Chen, Y Zhuge, H Chen, F Qian, K Zhou, C Niu, F Wang, …
- Journal: Cell Death & Disease (2019)
- Volume and Issue: 10(10)
- Pages: 778
- Citations: 190
- Year: 2019
- Contribution: The study investigates the role of pyroptosis in Kawasaki disease, highlighting the involvement of the HMGB1/RAGE/cathepsin B signaling pathway and NLRP3 inflammasome activation.
Title: Role of pyroptosis in cardiovascular diseases
- Authors: C Jia, H Chen, J Zhang, K Zhou, Y Zhuge, C Niu, J Qiu, X Rong, Z Shi, …
- Journal: International Immunopharmacology (2019)
- Volume: 67
- Pages: 311-318
- Citations: 180
- Year: 2019
- Contribution: This publication explores the role of pyroptosis in cardiovascular diseases, shedding light on the mechanisms involved in this form of programmed cell death.
Title: Role of pyroptosis in spinal cord injury and its therapeutic implications
- Authors: A Al Mamun, Y Wu, I Monalisa, C Jia, K Zhou, F Munir, J Xiao
- Journal: Journal of Advanced Research (2021)
- Volume: 28
- Pages: 97-109
- Citations: 100
- Year: 2021
- Contribution: The study discusses the role of pyroptosis in spinal cord injury and explores potential therapeutic implications for managing this condition.
Author Metrics:
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Citations:
- 3,047 citations by 2,694 documents
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Documents:
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h-index:
Research Timeline:
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2016.08~2020.12:
- Completed residency at the Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University.
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2016.08~2017.08:
- Served as a Visiting Fellow at the University of Maryland School of Medicine.
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2020.12~2022.12:
- Worked as a Lecturer at Wenzhou Medical University.
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2021.01~present:
- Currently serving as an Attending Physician at the Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University.
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2022.01~2022.12:
- Held the position of Associate Researcher at Wenzhou Medical University.
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2023.01~~present:
- Appointed as an Associate Professor and Researcher at Wenzhou Medical University.
