Chief scientist at React4life, Italy
Silvia Scaglione is a distinguished biomedical engineer and researcher with extensive experience in bioengineering, tissue engineering, and advanced in vitro models. She holds a Ph.D. in Bioengineering and Bioelectronics from the University of Genoa and has served as a researcher at the National Research Council (CNR) of Italy since 2010, currently holding a senior researcher position. She is the founder and Chief Scientist of React4Life, a startup focused on innovative 3D tissue models, and has led multiple high-impact research projects, including European-funded initiatives such as Horizon 2020 and HORIZON-HLTH. Her contributions to biomaterials, regenerative medicine, and organ-on-chip technologies have been recognized through numerous prestigious awards, including the Best Health Innovation award from the European Commission and the Gamma Donna award. Scaglione has been an invited speaker at major international conferences, a scientific evaluator for European research grants, and a reviewer for leading journals. With a strong publication record, patents, and leadership in academia and industry, she has significantly advanced biomedical research, particularly in cancer and regenerative medicine, making her a strong candidate for the Best Researcher Award.
Professional Profile
Education
Silvia Scaglione holds a Ph.D. in Bioengineering and Bioelectronics from the University of Genoa, where she also earned her Master’s degree in Biomedical Engineering. Her academic journey focused on advanced biomedical technologies, biomaterials, and tissue engineering, laying the foundation for her groundbreaking research in regenerative medicine and organ-on-chip models. Throughout her education, she developed expertise in computational modeling, microfluidics, and cellular biomechanics, which later became central to her work in both academia and industry. Her strong educational background has been instrumental in her role as a senior researcher at the National Research Council (CNR) of Italy and as the founder of React4Life, a startup specializing in innovative 3D tissue models for biomedical applications.
Professional Experience
Silvia Scaglione is a distinguished bioengineer with extensive experience in biomedical research and innovation. She serves as a senior researcher at the National Research Council (CNR) of Italy, where she focuses on tissue engineering, regenerative medicine, and organ-on-chip technologies. She is also the founder and president of React4Life, a biotech company specializing in advanced 3D tissue models for drug testing and personalized medicine. With a strong background in bioengineering, biomaterials, and microfluidics, she has led numerous research projects, published extensively in high-impact journals, and contributed to the development of cutting-edge biomedical technologies. Her expertise bridges academia and industry, driving forward innovative solutions in healthcare and life sciences.
Research Interest
Silvia Scaglione’s research interests lie at the intersection of bioengineering, regenerative medicine, and advanced in vitro modeling. She specializes in developing innovative 3D tissue models, organ-on-chip systems, and microfluidic platforms to improve drug testing, disease modeling, and personalized medicine. Her work focuses on creating physiologically relevant environments that mimic human tissues, enabling more accurate preclinical studies and reducing reliance on animal testing. Additionally, she explores biomaterials, stem cell therapies, and tissue regeneration strategies to advance medical treatments for various diseases. Through her research, she aims to bridge the gap between biomedical engineering and clinical applications, fostering the development of next-generation healthcare solutions.
Award and Honor
Silvia Scaglione has been recognized with several prestigious awards throughout her career, highlighting her contributions to biomedical engineering and innovation. In 2019, she received the ITWIIN Best Inventor Award for her development of MIVO, a patented technology that replicates living organs in the laboratory for testing purposes.In 2021, she was honored with the Women Startup Award powered by Intesa Sanpaolo Innovation Center, acknowledging her role as Chief Research Officer at React4Life and her innovative contributions to the biotech sector.The same year, React4Life, under her leadership, won the Innovation Radar Prize in the Health Tech Innovation category, further cementing her impact on advancing healthcare technologies.Additionally, she was a finalist for the GammaDonna Award in 2021, which celebrates innovative female entrepreneurship in Italy.
Conclusion
Silvia Scaglione is an exceptionally strong candidate for the Best Researcher Award. Her pioneering work in biomedical engineering, leadership in major research projects, industry impact, and multiple prestigious recognitions make her highly deserving of the award. Addressing publication metrics, broader global collaborations, and public science outreach could further solidify her standing in the global research community.
Publications Top Noted
-
Integrating bioprinted oral epithelium with millifluidics for fluorouracil perfusion and Fusobacterium infection to bioengineer oral mucositis-on-a-chip
- Authors: T.T. Truong, T.V. Phan, Y. Oo, O. Matangkasombut, J.N. Ferreira, et al.
- Year: 2025
- Citations: 0
-
Shifting the Focus from Dissolution to Permeation: Introducing the Meso-fluidic Chip for Permeability Assessment (MCPA)
- Authors: M.M. Tzanova, B.S. Larsen, R. Birolo, M. Hiorth, M.P. di Cagno, et al.
- Year: 2024
- Citations: 1
-
Fluid-Dynamic Culture of Tumour and Immune Cells for More Predictive Infiltration Studies and Immunotherapy Drug Screening
- Authors: M.E.F. Palamà, M. Aiello, S. Scaglione
- Year: Not specified
- Citations: 0
-
Multicompartmental dynamic models for permeability studies
- Authors: S. Scaglione, M.P. di Cagno
- Year: Not specified
- Citations: 0
-
3D Bioprinting as a Powerful Technique for Recreating the Tumor Microenvironment
- Authors: I. Parodi, D. Di Lisa, L. Pastorino, S. Scaglione, M.M. Fato
- Year: 2023
- Citations: 17
-
Different effects of NK cells and NK-derived soluble factors on cell lines derived from primary or metastatic pancreatic cancers
- Authors: P.F. Fiore, A.L. Di Pace, L.A. Conti, L. Moretta, P. Vacca, et al.
- Year: 2023
- Citations: 5
-
A Human Ovarian Tumor & Liver Organ-on-Chip for Simultaneous and More Predictive Toxo-Efficacy Assays
- Authors: A. Fedi, C. Vitale, M.M. Fato, S. Scaglione
- Year: 2023
- Citations: 10
-
Mathematical model of nutrients transport and cell growth in a bioprinted hydrogel
- Authors: I. Parodi, S. Scaglione, M.M. Fato, R. Repetto
- Year: Not specified
- Citations: 0
