Ahmet Altay | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

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Assoc. Prof. Dr. Ahmet Altay | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

Erzincan Üniversitesi, Turkey

Dr. Ahmet Altay is an accomplished researcher and academic in the field of chemistry, specializing in biochemistry, medicinal chemistry, and interdisciplinary sciences. With a strong background in natural product chemistry and anticancer drug discovery, he has contributed significantly to the scientific community through his research on antioxidants, cytotoxic agents, and enzyme inhibition. His extensive publication record in high-impact SCI-Expanded journals highlights his expertise in experimental and computational studies. Currently serving as an Associate Professor at Erzincan Binali Yıldırım University, Dr. Altay continues to push the boundaries of chemical and biochemical research, focusing on novel therapeutic compounds and their biological applications.

Professional Profile 

Education

Dr. Ahmet Altay earned his Ph.D. in Biochemistry from Middle East Technical University (METU), Turkey, in 2015. His doctoral research focused on the antioxidant and cytotoxic properties of Salvia fruticosa M., as well as its effects on cytochrome P450 enzymes and antioxidant gene expression in colon cancer cells.

Professional Experience

Dr. Altay has been a faculty member at Erzincan Binali Yıldırım University since 2016. He started as an Assistant Professor (2016-2018), was promoted to Associate Professor in 2020, and has since been actively involved in research and teaching. His work spans multiple disciplines within chemistry and biochemistry, with a strong focus on drug discovery and molecular interactions. His contributions include supervising graduate students, securing research grants, and collaborating on international scientific projects.

Research Interests

Dr. Ahmet Altay’s research interests lie at the intersection of biochemistry, medicinal chemistry, and pharmacology, with a particular focus on drug discovery and natural product chemistry. His work extensively explores the antioxidant, anticancer, and enzyme-inhibitory properties of bioactive compounds derived from medicinal plants. He is also deeply engaged in molecular docking studies to understand drug-receptor interactions at a computational level. Additionally, his research investigates apoptosis mechanisms, oxidative stress-related disorders, and the modulation of key metabolic pathways in cancer and neurodegenerative diseases. By integrating experimental and computational approaches, Dr. Altay aims to develop novel therapeutic agents that can target cancer, microbial infections, and enzyme-related disorders. His interdisciplinary research combines chemical synthesis, molecular modeling, and pharmacological evaluation to provide innovative solutions in biomedical sciences.

Awards and Honors

Dr. Ahmet Altay has received multiple awards and recognitions for his outstanding contributions to scientific research and academia. His excellence in publishing high-impact research has been acknowledged with best paper awards and recognitions from international conferences and scientific organizations. He has been honored with research grants and funding support for his projects on natural product chemistry and drug discovery. As an active academic, he has also received accolades for his contributions to student mentorship and scientific collaboration. His efforts in cancer research and enzyme inhibition studies have been recognized by national and international institutions. Additionally, his role as a peer reviewer and editorial board member in prestigious scientific journals highlights his expertise and influence in the field. These awards and honors underscore his dedication to advancing biomedical and pharmaceutical sciences.

Research Skills

Dr. Ahmet Altay possesses a diverse set of research skills spanning experimental and computational methodologies. His expertise includes the isolation and structural characterization of bioactive natural products using advanced chromatographic and spectroscopic techniques such as HPLC, GC-MS, and NMR. He is highly proficient in molecular docking, molecular dynamics simulations, and in silico drug design to predict ligand-target interactions. His skills in biochemical assays enable the evaluation of antioxidant, antimicrobial, and anticancer activities of synthetic and natural compounds. Additionally, he has extensive experience in enzyme kinetics, apoptosis studies, and gene expression analysis using RT-PCR and Western blot techniques. His interdisciplinary knowledge allows him to integrate synthetic chemistry, pharmacology, and bioinformatics to address complex biomedical challenges. Dr. Altay’s strong analytical skills, coupled with his experience in mentoring and collaboration, make him a leading researcher in his field.

Conclusion

Dr. Ahmet Altay is a strong candidate for the Best Researcher Award due to his high research output, international collaborations, and contributions to anticancer and biochemical research. To enhance his profile further, he could focus on leading large-scale projects, securing more grants, and publishing in top-tier journals. Nonetheless, his achievements make him a compelling nominee for this award.

Publications Top Noted

  • Title: Diffractaic acid exerts anti-cancer effects on hepatocellular carcinoma HepG2 cells by inducing apoptosis and suppressing migration through targeting thioredoxin reductase 1

    • Authors: Emine Karaca Sulukoğlu, Şükran Günaydın, Şeyda Nur Kalın, Ahmet Altay, Harun Budak
    • Year: 2024
    • Citation: Naunyn-Schmiedeberg’s Archives of Pharmacology
    • DOI: 10.1007/s00210-024-02980-5

  • Title: The Combined Effect of Vulpinic Acid and Doxorubicin in Breast Cancer MCF-7 Cells

    • Authors: Esma Kübra Kağan Yeniçeri, Ahmet Altay
    • Year: 2024
    • Citation: Erzincan Üniversitesi Fen Bilimleri Enstitüsü Dergisi
    • DOI: 10.18185/erzifbed.1376859

  • Title: Diffractaic acid exhibits thioredoxin reductase 1 inhibition in lung cancer A549 cells

    • Authors: Şükran Günaydın, Emine Karaca Sulukoğlu, Şeyda Nur Kalın, Ahmet Altay, Harun Budak
    • Year: 2023
    • Citation: Journal of Applied Toxicology
    • DOI: 10.1002/jat.4505

  • Title: Effect of evernic acid on human breast cancer MCF‐7 and MDA‐MB‐453 cell lines via thioredoxin reductase 1: A molecular approach

    • Authors: Şeyda Nur Kalın, Ahmet Altay, Harun Budak
    • Year: 2023
    • Citation: Journal of Applied Toxicology
    • DOI: 10.1002/jat.4451

  • Title: In Vitro Cytotoxic Evaluation of a Silver(I) Complex Including Non-Steroidal Anti-Inflammatory Drug Niflumic Acid and 3-Picoline on Human-Derived Cancer Cell Lines

    • Authors: Sema Çağlar, Ahmet Altay, Bülent Çağlar, Esma Kübra Kağan Yeniçeri, Betül Harurluoğlu
    • Year: 2022
    • Citation: Erzincan Üniversitesi Fen Bilimleri Enstitüsü Dergisi
    • DOI: 10.18185/erzifbed.1130634

  • Title: A Biochemical Approach for Hedysarum candidissimum from Turkey: Screening Phytochemicals, Evaluation of Biological Activities, and Molecular Docking Study

    • Authors: Ahmet Altay, Esma Yeniceri, Parham Taslimi, Tugba Taskin‐Tok, Mustafa Abdullah Yilmaz, Ekrem Koksal
    • Year: 2022
    • Citation: Chemistry & Biodiversity
    • DOI: 10.1002/cbdv.202200348

  • Title: Phytochemical Analysis and Biological Evaluation of Hypericum linarioides Bosse: in Vitro and in Silico Studies

    • Authors: Ahmet Altay, Esma Kübra Kağan Yeniçeri, Parham Taslimi, Tugba Taskin‐Tok, Mustafa Abdullah Yılmaz, Ekrem Köksal
    • Year: 2022
    • Citation: ChemistrySelect
    • DOI: 10.1002/slct.202200039

Jessie Santoro | Biochemistry | Best Researcher Award

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🌟Dr. Jessie Santoro, Biochemistry, Best Researcher Award🏆

  •   Doctorate at IRCCS SYNLAB SDN, Italy

Jessie Santoro, PhD, is a dedicated and enthusiastic research biologist with a strong background in molecular biology and extracellular vesicles (EVs). Dr. Santoro has extensive experience in scientific research, particularly in biomedicine, focusing on the utilization of EVs for diagnostic applications. With a passion for advancing knowledge in her field, she has contributed significantly to scientific literature through publications and presentations at conferences. Dr. Santoro is known for her excellent organizational and communication skills, as well as her ability to lead and work effectively within multidisciplinary teams.

Author Metrics

Scopus Profile

Dr. Santoro’s research impact is reflected in her author metrics, including citation counts and journal impact factors. Her publications in high-impact journals such as Food Chemistry have garnered attention within the scientific community, demonstrating the relevance and significance of her research in the field of molecular biology and biomedicine.

  • Citations: 25
  • Documents: 18
  • h-index: 3

Citations

Jessie Santoro’s research has received a total of 25 citations across 18 documents.

h-index

The h-index, an indicator of research impact, is calculated as 3 for Jessie Santoro.

Education

Dr. Jessie Santoro obtained her PhD in Pharmacy and Pharmaceutical Sciences from Trinity College Dublin in 2023. Prior to her doctoral studies, she earned a Master’s degree in Reproductive and Developmental Biology from the University of Napoli “Federico II” and a Bachelor’s degree in Biological Sciences from the University of Campania “Luigi Vanvitelli.”

Research Focus

Dr. Santoro’s research focuses on the characterization and application of extracellular vesicles (EVs) in biomedicine. Specifically, she has explored the composition of human milk EVs to improve infant milk formula. Her work involves advanced techniques in EV separation, characterization, and functional assays, with the ultimate goal of developing diagnostic tools and therapeutic applications.

Professional Journey

Dr. Santoro’s professional journey includes diverse experiences in research and academia. She has served as a postdoctoral researcher at IRCCS SYNLAB SDN in Napoli, where she conducts scientific and clinical research in biomedicine. Prior to this, she worked as a PhD researcher at Trinity College Dublin, where she investigated human milk composition and mentored undergraduate students. Dr. Santoro has also undertaken research internships at institutions such as the University of Eastern Finland and EMBL Heidelberg, gaining valuable expertise in EV biology and molecular medicine.

Honors & Awards

Throughout her career, Dr. Santoro has received recognition for her research contributions. She has been awarded certificates for her participation in prestigious training programs, including the EMBO Practical Course on Extracellular Vesicles and the Clinical Research Development Ireland program. Additionally, her publications in reputable journals such as Food Chemistry highlight the significance of her work in the scientific community.

Publications & Contributions

Dr. Santoro has made significant contributions to the scientific literature through her publications and presentations. Her research findings have been published in peer-reviewed journals, including Food Chemistry and STAR Protocol, addressing key aspects of EV biology and application. Moreover, Dr. Santoro has presented her work at conferences and symposiums, fostering collaboration and knowledge exchange within the scientific community.

1. Title: An investigation of extracellular vesicles in bovine colostrum, first milk and milk over the lactation curve

  • Authors: Santoro, J., Mukhopadhya, A., Oliver, C., … Giblin, L., O’Driscoll, L.
  • Journal: Food Chemistry
  • Year: 2023
  • Volume: 401
  • Pages: 134029
  • Open Access: Yes
  • Citations: 8

Abstract: This article investigates extracellular vesicles in bovine colostrum, first milk, and milk over the lactation curve. The study explores the composition and characteristics of these vesicles, shedding light on their potential roles in nutrition and health.

2. Title: Extracellular vesicle separation from milk and infant milk formula using acid precipitation and ultracentrifugation

  • Authors: Mukhopadhya, A., Santoro, J., O’Driscoll, L.
  • Journal: STAR Protocols
  • Year: 2021
  • Volume: 2(4)
  • Pages: 100821
  • Open Access: Yes
  • Citations: 6

Abstract: This article presents a protocol for separating extracellular vesicles from milk and infant milk formula using acid precipitation and ultracentrifugation. The protocol provides a valuable tool for researchers studying these vesicles and their applications in various fields.

3. Title: Optimisation and comparison of orthogonal methods for separation and characterisation of extracellular vesicles to investigate how representative infant milk formula is of milk

  • Authors: Mukhopadhya, A., Santoro, J., Moran, B., Useckaite, Z., O’Driscoll, L.
  • Journal: Food Chemistry
  • Year: 2021
  • Volume: 353
  • Pages: 129309
  • Open Access: Yes
  • Citations: 15

Abstract: This article optimizes and compares orthogonal methods for the separation and characterization of extracellular vesicles to investigate the representativeness of infant milk formula compared to milk. The study provides insights into the composition and properties of these vesicles, informing research in the field of nutrition and infant health.

Research Timeline

  • 2011-2015: Bachelor’s degree in Biological Sciences from the University of Campania “Luigi Vanvitelli.”
  • 2016-2018: Master’s degree in Reproductive and Developmental Biology from the University of Napoli “Federico II.”
  • 2016-2017: Research trainee at the University of Eastern Finland, focusing on extracellular vesicles from culture media.
  • 2018-2023: PhD researcher at Trinity College Dublin, investigating human milk composition for improving infant milk formula.
  • 2019: Research trainee at EMBL Heidelberg, participating in a practical course on extracellular vesicles.
  • 2020: Training for infant milk formula manufacturing at Teagasc, Ireland.
  • 2023-present: Postdoctoral researcher at IRCCS SYNLAB SDN, conducting scientific and clinical research in biomedicine.

This timeline outlines Dr. Santoro’s academic and research journey, highlighting her progression from undergraduate studies to postdoctoral research in the field of molecular biology and extracellular vesicles.