Assoc. Prof. Dr. Hao Wu | Protein engineering | Best Researcher Award
Teacher at Changsha University of Science and Technology, China
Dr. Hao Wu is a highly qualified researcher with a Ph.D. in Microbiology and extensive postdoctoral experience. Currently serving as an Associate Professor at Changsha University of Science & Technology, his research focuses on food biotechnology, protein engineering, and synthetic biology, particularly in the development of anti-diabetic compounds, enzyme engineering, and the production of human milk oligosaccharides. With over 20 publications in high-impact journals and leadership in numerous first-author and corresponding author roles, Dr. Wu has made significant contributions to applied food science and biotechnology. His work on enzyme stability and microbial fermentation has direct industrial and health-related implications. Additionally, he is actively involved in peer review and editorial positions for several prestigious journals. While his profile would benefit from further recognition through awards and major project leadership, his impressive publication record and research contributions make him a strong contender for the Best Researcher Award.
Professional Profile
Education🎓
Dr. Hao Wu holds a Ph.D. in Microbiology, which he earned in 2019 from Guangxi University in Nanning, Guangxi, China. He also completed his Bachelor of Science in Bioengineering at Guangxi University in 2013. His academic background provides a solid foundation for his current research, bridging microbiology, biotechnology, and food science. During his doctoral studies, Dr. Wu specialized in the molecular aspects of food biotechnology and protein engineering, laying the groundwork for his postdoctoral research at Jiangnan University. This advanced training has been crucial in shaping his research focus on the production of anti-diabetic compounds, enzyme modification, and synthetic biology applications. Throughout his academic journey, Dr. Wu has gained a strong grasp of both theoretical and practical aspects of bioengineering, allowing him to make significant contributions to the field of food biotechnology. His educational path reflects a deep commitment to advancing the understanding of microbiology and food science.
Professional Experience📝
Dr. Hao Wu has a rich professional background, combining research and teaching roles in the field of food biotechnology. After completing his Ph.D., he gained postdoctoral experience at Jiangnan University, where he advanced his research in protein engineering and microbial fermentation techniques. In December 2021, Dr. Wu joined Changsha University of Science & Technology as an Associate Professor in the School of Food Science and Bioengineering, where he has continued his research on food biotechnology, synthetic biology, and enzyme engineering. His work focuses on developing innovative solutions such as producing anti-diabetic compounds through microbial fermentation and engineering enzymes for the production of functional sugars and sugar alcohols. Dr. Wu’s role as a professor also involves mentoring graduate students and contributing to the university’s research initiatives. His experience as a peer reviewer and editorial board member for numerous scientific journals further highlights his active engagement in the scientific community.
Research Interest🔎
Dr. Hao Wu’s research interests are centered around food biotechnology, protein engineering, fermentation engineering, and synthetic biology. His work focuses on the development of potential anti-diabetic compounds through microbial fermentation techniques, employing methods such as microbial mutation breeding and fermentation process control. Additionally, Dr. Wu is dedicated to the molecular modification of enzymes, particularly in improving their thermal stability, catalytic activity, and substrate specificity for the production of functional sugars and sugar alcohols. Another key area of his research involves using cutting-edge synthetic biological technologies, including gene editing and metabolic engineering, to design and construct efficient cell factories for producing human milk oligosaccharides. His innovative approaches aim to address pressing challenges in the food industry, including the creation of healthier food ingredients and more sustainable production methods. Dr. Wu’s interdisciplinary expertise allows him to make significant contributions to both the scientific community and the applied biotechnology sector.
Award and Honor🏆
Dr. Hao Wu has earned several notable awards and honors throughout his academic and professional career, reflecting his outstanding contributions to the fields of food biotechnology and microbiology. As a leading researcher in the production of functional food ingredients and enzyme engineering, he has gained recognition for his innovative work, particularly in developing anti-diabetic compounds through microbial fermentation and engineering enzymes with improved properties. His research has been widely published in prestigious journals, and his work has attracted significant attention from the scientific community. Dr. Wu’s leadership extends beyond research, as he serves as a peer reviewer for numerous scientific journals, such as Journal of Agricultural and Food Chemistry and Critical Reviews in Food Science and Nutrition. His expertise has also led to editorial roles, including membership on the editorial boards of Food Science and Human Wellness and Journal of Future Foods, further demonstrating his respected status in the field.
Research Skill🔬
Dr. Hao Wu possesses a diverse set of research skills that have significantly contributed to his success in food biotechnology and microbiology. His expertise spans several advanced techniques, including microbial fermentation, protein engineering, and enzyme modification. Dr. Wu is proficient in employing microbial mutation breeding and fermentation process control to produce bioactive compounds, particularly for anti-diabetic applications. His work in molecular modification of enzymes focuses on improving their thermal stability, catalytic activity, and substrate specificity, using cutting-edge approaches like computational design and rational engineering. In addition, Dr. Wu is well-versed in synthetic biology techniques, such as gene editing and metabolic engineering, which he uses to design high-efficiency cell factories for the production of human milk oligosaccharides. His ability to integrate various biotechnological methodologies, along with his comprehensive understanding of biochemistry, enables him to address complex challenges and make innovative contributions to both the scientific community and the food industry.
Conclusion💡
Dr. Hao Wu is a strong candidate for the Best Researcher Award, particularly due to his:
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High-quality publications,
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Pioneering work in enzyme and metabolic engineering,
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Leadership in synthetic biology applications for food science, and
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Active contribution to the academic community through editorial roles.
If complemented by evidence of major grant leadership, mentorship of young researchers, and international academic visibility, his candidacy would be even more compelling.
Publications Top Noted✍️
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Research Progress on the Preparation and Function of Antioxidant Peptides from Walnuts
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Authors: Yuxi Hu, Ce Ni, Yingying Wang, Xun Yu, Hao Wu, Jia Tu, Changzhu Li, Zhihong Xiao, Li Wen
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Year: 2023
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Citation: International Journal of Molecular Sciences, DOI: 10.3390/ijms241914853
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D-allulose, a Versatile Rare Sugar: Recent Biotechnological Advances and Challenges
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Authors: Wenli Zhang, Ding Chen, Jiajun Chen, Wei Xu, Qiuming Chen, Hao Wu, Cuie Guang, Wanmeng Mu
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Year: 2023
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Citation: Critical Reviews in Food Science and Nutrition, DOI: 10.1080/10408398.2021.2023091
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Engineering the Thermostability of D-lyxose Isomerase from Caldanaerobius Polysaccharolyticus via Multiple Computer-Aided Rational Design for Efficient Synthesis of D-Mannose
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Authors: Hao Wu, Ming Yi, Xiaoyi Wu, Yating Ding, Minghui Pu, Li Wen, Yunhui Cheng, Wenli Zhang, Wanmeng Mu
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Year: 2023
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Citation: Synthetic and Systems Biotechnology, DOI: 10.1016/j.synbio.2023.04.003
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Overview of Strategies for Developing High Thermostability Industrial Enzymes: Discovery, Mechanism, Modification and Challenges
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Authors: Hao Wu, Qiuming Chen, Wenli Zhang, Wanmeng Mu
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Year: 2023
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Citation: Critical Reviews in Food Science and Nutrition, DOI: 10.1080/10408398.2021.1970508
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Alanine Substitution to Determine the Effect of LR5 and YR6 Rice Peptide Structure on Antioxidant and Anti-Inflammatory Activity
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Authors: Yun-Hui Cheng, Bu-Qing Liu, Bo Cui, Li Wen, Zhou Xu, Mao-Long Chen, Hao Wu
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Year: 2023
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Citation: Nutrients, DOI: 10.3390/nu15102373
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Recent Development of Phenyllactic Acid: Physicochemical Properties, Biotechnological Production Strategies and Applications
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Authors: Hao Wu, Cuie Guang, Wenli Zhang, Wanmeng Mu
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Year: 2023
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Citation: Critical Reviews in Biotechnology, DOI: 10.1080/07388551.2021.2010645
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Application Prospects and Opportunities of Inorganic Nanomaterials for Enzyme Immobilization in the Food-Processing Industry
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Authors: Hao Wu, Wanmeng Mu
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Year: 2022
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Citation: Current Opinion in Food Science, DOI: 10.1016/j.cofs.2022.100909
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Glycosyltransferase from Bacteroides Gallinaceum Is a Novel α-1,3-Fucosyltransferase That Can Be Used for 3-Fucosyllactose Production In Vivo by Metabolically Engineered Escherichia Coli
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Authors: Geng Chen, Hao Wu, Yingying Zhu, Li Wan, Wenli Zhang, Wanmeng Mu
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Year: 2022
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Citation: Journal of Agricultural and Food Chemistry, DOI: 10.1021/acs.jafc.1c06719
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D-Mannose-Producing Isomerases and Epimerases: Properties, Comparisons, and Different Strategies
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Authors: Hao Wu
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Year: 2021
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Citation: Novel Enzymes for Functional Carbohydrates Production, DOI: 10.1007/978-981-33-6021-1_3
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L-Arabinose Isomerase: Sources, Biochemical Properties, and Its Use to Produce D-Tagatose
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Authors: Hao Wu
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Year: 2021
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Citation: Novel Enzymes for Functional Carbohydrates Production, DOI: 10.1007/978-981-33-6021-1_4
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Engineering Escherichia Coli for Highly Efficient Production of Lacto-N-triose II from N-acetylglucosamine, the Monomer of Chitin
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Authors: Hao Wu
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Year: 2021
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Citation: Biotechnology for Biofuels, DOI: 10.1186/s13068-021-02050-5
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Efficient Control of Acrylamide in French Fries by an Extraordinarily Active and Thermo-Stable L-Asparaginase: A Lab-Scale Study
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Authors: Hao Wu
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Year: 2021
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Citation: Food Chemistry, DOI: 10.1016/j.foodchem.2021.130046
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Microbial Production, Molecular Modification, and Practical Application of L-Asparaginase: A Review
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Authors: Hao Wu
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Year: 2021
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Citation: International Journal of Biological Macromolecules, DOI: 10.1016/j.ijbiomac.2021.07.107
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Metabolic Engineering of Escherichia Coli for Efficient Biosynthesis of Lacto-N-tetraose Using a Novel β-1,3-Galactosyltransferase from Pseudogulbenkiania Ferrooxidans
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Authors: Hao Wu
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Year: 2021
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Citation: Journal of Agricultural and Food Chemistry, DOI: 10.1021/acs.jafc.1c04059
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Metabolic Engineering of Escherichia Coli for Lacto-N-triose II Production with High Productivity
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Authors: Hao Wu
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Year: 2021
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Citation: Journal of Agricultural and Food Chemistry, DOI: 10.1021/acs.jafc.1c00246
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