Prof. Toshiharu Shinoka | Medicine and Dentistry | Excellence in Research
Professor of Surgery at Nationwide Children’s Hospital, United States
Dr. Toshiharu Shinoka, M.D., Ph.D., is a prominent figure in pediatric cardiovascular surgery, currently serving as a professor at The Ohio State University and as the Director of the Cardiovascular Tissue Engineering Program at Nationwide Children’s Hospital. He received his M.D. from Hiroshima University and his Ph.D. from Tokyo Women’s Medical University. With extensive experience in both clinical practice and research, Dr. Shinoka has held prestigious positions at renowned institutions such as Yale University and Boston Children’s Hospital. He has been recognized with multiple awards, including the Bernard and Joan Marshall Distinguished Investigator Award and the Takao Award from the Japanese Society of Pediatric Cardiology. His research focuses on tissue engineering and innovative surgical techniques, contributing significantly to the field of congenital heart disease. Dr. Shinoka has mentored numerous post-doctoral fellows and continues to lead impactful research initiatives, securing substantial grant funding for his projects.
Professional Profile:
Education🎓
Dr. Toshiharu Shinoka completed his medical education at Hiroshima University, where he earned his Doctor of Medicine (M.D.) degree. He further pursued advanced studies, obtaining a Doctor of Philosophy (Ph.D.) from Tokyo Women’s Medical University. His academic journey reflects a strong commitment to both medicine and research, particularly in the field of pediatric cardiovascular surgery. Following his medical training, Dr. Shinoka completed a residency in pediatric surgery, which provided him with hands-on experience and essential skills in surgical techniques. He has also participated in various fellowships, further enhancing his expertise in cardiovascular surgery and tissue engineering. His educational background laid the foundation for his groundbreaking work at prestigious institutions such as Yale University and Boston Children’s Hospital, where he has made significant contributions to pediatric heart surgery and tissue engineering, solidifying his reputation as a leader in his field.
Professional Experience 💼
Dr. Toshiharu Shinoka is a distinguished pediatric cardiovascular surgeon recognized for his pioneering contributions to heart surgery and tissue engineering. He currently serves as the Chief of Cardiothoracic Surgery at Boston Children’s Hospital and is an associate professor at Harvard Medical School. Dr. Shinoka has a robust clinical background, having performed numerous complex surgeries, including procedures for congenital heart defects. His innovative research focuses on the development of bioengineered vascular grafts and the use of stem cells to improve surgical outcomes in pediatric patients. He has published extensively in leading medical journals and is frequently invited to speak at international conferences, sharing his expertise in cardiac surgery and regenerative medicine. Additionally, Dr. Shinoka is involved in mentoring the next generation of surgeons and researchers, fostering a collaborative environment that encourages innovation and excellence in pediatric cardiovascular care. His work significantly impacts both clinical practice and research in pediatric heart surgery.
Research Interest🔍
Dr. Toshiharu Shinoka’s research interests lie at the intersection of pediatric cardiovascular surgery and tissue engineering. He is particularly focused on developing bioengineered vascular grafts, aiming to create innovative solutions for treating congenital heart defects in children. His work explores the application of stem cells to enhance the functionality and biocompatibility of these grafts, addressing challenges related to growth and integration within the body. Dr. Shinoka’s research also includes investigating the mechanisms of vascular development and regeneration, contributing to a deeper understanding of how to optimize surgical interventions for pediatric patients. Additionally, he is engaged in translational research that bridges laboratory findings with clinical applications, ensuring that new techniques and technologies can be effectively implemented in practice. Through his work, Dr. Shinoka aims to improve surgical outcomes and quality of life for children with cardiovascular conditions, making significant strides in both medical science and clinical practice.
Conclusion
Toshiharu Shinoka, M.D., Ph.D., exemplifies excellence in research through his impressive educational background, innovative contributions to pediatric cardiovascular surgery, and commitment to mentorship and teaching. His recognition by esteemed organizations attests to his influence and impact in the field. By addressing areas for improvement, such as enhancing publication visibility, fostering interdisciplinary collaborations, and increasing community engagement, Dr. Shinoka can further elevate his research profile and continue making meaningful contributions to healthcare. Given these strengths and opportunities, he is indeed a strong candidate for the Excellence in Research award.
Publications top noted📜
- Tissue engineering heart valves: valve leaflet replacement study in a lamb model
Authors: T Shinoka, CK Breuer, RE Tanel, G Zund, T Miura, PX Ma, R Langer, …
Year: 1995 📅
Citation: The Annals of Thoracic Surgery 60, S513-S516
Citations: 675 📊 - Creation of viable pulmonary artery autografts through tissue engineering
Authors: T Shinoka, D Shum-Tim, PX Ma, RE Tanel, N Isogai, R Langer, JP Vacanti, …
Year: 1998 📅
Citation: The Journal of Thoracic and Cardiovascular Surgery 115 (3), 536-546
Citations: 636 📊 - Tissue-engineered vascular grafts transform into mature blood vessels via an inflammation-mediated process of vascular remodeling
Authors: JD Roh, R Sawh-Martinez, MP Brennan, SM Jay, L Devine, DA Rao, T Yi, …
Year: 2010 📅
Citation: Proceedings of the National Academy of Sciences 107 (10), 4669-4674
Citations: 618 📊 - Late-term results of tissue-engineered vascular grafts in humans
Authors: N Hibino, E McGillicuddy, G Matsumura, Y Ichihara, Y Naito, C Breuer, …
Year: 2010 📅
Citation: The Journal of Thoracic and Cardiovascular Surgery 139 (2), 431-436. e2
Citations: 600 📊 - Tissue engineering of autologous aorta using a new biodegradable polymer
Authors: D Shum-Tim, U Stock, J Hrkach, T Shinoka, J Lien, MA Moses, A Stamp, …
Year: 1999 📅
Citation: The Annals of Thoracic Surgery 68 (6), 2298-2304
Citations: 465 📊 - Tissue-engineered heart valves. Autologous valve leaflet replacement study in a lamb model.
Authors: T Shinoka, PX Ma, D Shum-Tim, CK Breuer, RA Cusick, G Zund, R Langer, …
Year: 1996 📅
Citation: Circulation 94 (9 Suppl), II164-8
Citations: 426 📊 - First evidence that bone marrow cells contribute to the construction of tissue-engineered vascular autografts in vivo
Authors: G Matsumura, S Miyagawa-Tomita, T Shin’oka, Y Ikada, H Kurosawa
Year: 2003 📅
Citation: Circulation 108 (14), 1729-1734
Citations: 392 📊 - Vascular tissue engineering: towards the next generation vascular grafts
Authors: Y Naito, T Shinoka, D Duncan, N Hibino, D Solomon, M Cleary, A Rathore, …
Year: 2011 📅
Citation: Advanced Drug Delivery Reviews 63 (4-5), 312-323
Citations: 297 📊 - Cell-seeding techniques in vascular tissue engineering
Authors: GA Villalona, B Udelsman, DR Duncan, E McGillicuddy, …
Year: 2010 📅
Citation: Tissue Engineering Part B: Reviews 16 (3), 341-350
Citations: 289 📊 - A critical role for macrophages in neovessel formation and the development of stenosis in tissue-engineered vascular grafts
Authors: N Hibino, T Yi, DR Duncan, A Rathore, E Dean, Y Naito, A Dardik, …
Year: 2011 📅
Citation: The FASEB Journal 25 (12), 4253
Citations: 262 📊 - Concise review: tissue-engineered vascular grafts for cardiac surgery: past, present, and future
Authors: H Kurobe, MW Maxfield, CK Breuer, T Shinoka
Year: 2012 📅
Citation: Stem Cells Translational Medicine 1 (7), 566-571
Citations: 197 📊 - Tissue-engineered small diameter arterial vascular grafts from cell-free nanofiber PCL/chitosan scaffolds in a sheep model
Authors: T Fukunishi, CA Best, T Sugiura, T Shoji, T Yi, B Udelsman, D Ohst, …
Year: 2016 📅
Citation: PLoS One 11 (7), e0158555
Citations: 195 📊 - The in vitro construction of a tissue engineered bioprosthetic heart valve
Authors: G Zund, CK Breuer, T Shinoka, PX Ma, R Langer, JE Mayer, JP Vacanti
Year: 1997 📅
Citation: European Journal of Cardio-Thoracic Surgery 11 (3), 493-497
Citations: 195 📊 - Tissue-engineered vascular grafts demonstrate evidence of growth and development when implanted in a juvenile animal model
Authors: MP Brennan, A Dardik, N Hibino, JD Roh, GN Nelson, X Papademitris, …
Year: 2008 📅
Citation: Annals of Surgery 248 (3), 370-377
Citations: 171 📊 - Tissue-engineered heart valve leaflets: does cell origin affect outcome?
Authors: T Shinoka, D Shum-Tim, PX Ma, RE Tanel, R Langer, JP Vacanti, …
Year: 1997 📅
Citation: Circulation 96 (9 Suppl), II-102
Citations: 163 📊