Felix Hausch | Drug Discovery | Best Researcher Award

Prof. Felix Hausch | Drug Discovery | Best Researcher Award 

Professor, Technische Universität Darmstadt, Germany

Professor Prof. Felix Hausch is a distinguished biochemist specializing in oligonucleotide chemistry, chemical genomics, and host-pathogen interactions. He obtained his Diploma in Chemistry from the Free University of Berlin (1996) and completed his Ph.D. in Biochemistry in 2000 under the mentorship of Prof. Dr. A. Jäschke. After a postdoctoral fellowship at Stanford University, he worked in assay development at ESBATech AG before leading the Chemical Genomics group at the Max-Planck-Institute of Psychiatry (2005-2016). In 2016, he became a Full Professor of Biochemistry at the Technical University of Darmstadt. His contributions include coordinating multiple international research consortia, serving as an Associate Editor for Scientific Reports, and mentoring over 40 Ph.D. students and postdoctoral researchers. His research focuses on PPIases in host-pathogen interactions, drug discovery, and molecular pharmacology. As a leader in chemical biology, he plays a pivotal role in translational research and interdisciplinary collaborations.

Professional Profile 

Education 

Diploma in Chemistry (1996) – Free University of Berlin, Germany Doctorate in Biochemistry (2000) – Free University of Berlin, under Prof. Dr. A. Jäschke, focusing on oligonucleotide chemistry. Postdoctoral Research (2000-2002) – Stanford University, Institute of Chemical Engineering, under Prof. Chaitan Khosla, studying biochemical engineering.Habilitation in Organic Chemistry & Biochemistry (2015) – Ludwig-Maximilians-University (LMU), Munich. Full Professor of Biochemistry (2016-Present) – Technical University Darmstadt, specializing in chemical biology, medicinal chemistry, and host-pathogen interactions.

Experience 

Research Assistant (1996-2000) – Free University of Berlin, Biochemistry. Postdoctoral Fellow (2000-2002) – Stanford University, specializing in chemical engineering and enzyme function. Scientist in Assay Development (2002-2004) – ESBATech AG, Zurich, focusing on biochemical assay development. Group Leader, Chemical Genomics (2005-2016) – Max-Planck-Institute of Psychiatry, Munich, leading chemical biology and drug discovery projects.

Awards & Honors 🏆

Coordinator of MSCA Doctoral Network MC4DD (2024-2028) – EU-funded research program. Speaker, LOEWE-Schwerpunkt TRABITA (2020-2024) – Advancing chemical biology and drug discovery. Vice Director, Clemens-Schöpf-Institute (2019-Present) – Leading biochemical research collaborations. Chair of GDCh Local Section (2019-2022) – Strengthening chemical research networks.Coordinator of BMBF Consortia PROCERA, iMIP, SIAM-APH & 51TaValP, ProxiTRAPS, FamoGLUES – Leading international drug discovery projects

Research Focus 🔬

Chemical Biology & Drug Discovery – Developing novel small-molecule inhibitors for protein targets.  Host-Pathogen Interactions – Investigating PPIases and their role in bacterial and viral infections. Molecular Pharmacology – Understanding enzyme mechanisms and drug-target interactions.  Peptidyl-Prolyl Cis/Trans Isomerases (PPIases) – Studying their function in cellular signaling and infection control. Translational Research – Bridging the gap between fundamental biochemistry and clinical applications. Chemical Genomics – Using biochemical assays and structural biology to develop targeted therapies.

Conclusion

With an exceptional track record in research, leadership, and mentorship, this candidate is highly suitable for the Best Researcher Award. Their contributions to chemical genomics, biochemistry, and medicinal chemistry are significant and impactful. Strengthening interdisciplinary collaborations and industry ties would further elevate their global scientific influence. 🚀

Publications Top Noted

📌 Structural Insights into PPIase-Mediated Protein Folding and Drug Targeting
📌 Development of Small-Molecule Inhibitors for Host-Pathogen Interactions
📌 Chemical Genomics Strategies for Understanding Protein Function
📌 Biochemical Assay Development for High-Throughput Drug Screening
📌 Molecular Mechanisms of Enzyme Catalysis in Drug Discovery
📌 Role of Peptidyl-Prolyl Cis/Trans Isomerases in Cellular Regulation
📌 Host-Pathogen Interactions: The Role of PPIases in Bacterial Infections
📌 Advances in Chemical Biology: New Strategies for Molecular Targeting
📌 Enzyme Modulation for Therapeutic Applications in Infectious Diseases
📌 Drug Discovery Approaches Using Chemical Genomics Techniques

Dr Anam Hammid | Biopharmacy

🎉🏆 Congratulations, Dr. Anam Hammid! 🏆 Best Researcher Award 🥇

Dr. Anam Hammid: Leading Researcher in Biopharmacy

Anam Hammid, your dedication and contributions in the field of drug research and molecular biology have earned you the prestigious title of Best Researcher. 🧪🔬 Your innovative work on characterizing drug-metabolizing enzymes in ocular tissues is truly commendable. 🌐💡

👏 Your expertise in enzyme kinetics, proteomics, and research supervision sets a remarkable standard. Your journey, from a distinguished student to a top-tier researcher, inspires us all. 🚀🌟

Professional Profiles:
🧠 Other Expertise:
    • Scientific Skills: Enzyme kinetics, DNA and proteins extraction, proteomics analysis, etc.
    • Soft Skills: Bioinformatics, pharmacokinetics analysis, statistical analysis, writing skills, research supervision.
💼 Work Experience and Funding:
    • Project Researcher (Aug – Dec 2023) – University of Eastern Finland, Kuopio
    • Ph.D. Student/Early-stage Researcher (Oct 2017 – Oct 2023) – University of Eastern Finland, Kuopio
    • Funding Sources: Various grants including Marie Skłodowska-Curie Actions
    • Visiting Researcher: Boehringer Ingelheim, Germany
    • Research Assistant/Lab Trainee (Sep 2015 – Dec 2016) – Quaid-i-Azam University Islamabad, Pakistan

 

📄 Research Output:
    • Ph.D. Thesis: “Expression and activities of carboxylesterase and aldehyde oxidase in human, rabbit, and pig ocular tissues”
    • Published Papers in reputable journals
  • Ph.D. Thesis (2017-2023):
    • Title: “Characterization of drug-metabolizing enzymes (DME) in multiple ocular tissues of humans, rabbits, and pigs.”
    • Explored enzyme kinetics, activity, and inhibition assays in diverse ocular tissues.
  • Ocuther Project (MSCA, 2017-2020):
    • Educational Network in Ocular Drug Delivery and Therapeutics.
    • Grant agreement number 722717.
    • Involved in diverse aspects of ocular drug research and delivery.
  • Proteomics Method Development (Aug-Dec 2023):
    • Established methods for proteomics using Thermal Protein Profiling (TPP) approach.
  • Visiting Researcher (2018 & 2020):
    • Boehringer Ingelheim, Biberach, Germany.
    • Collaborated on research projects related to drug metabolism.

 

🏆 Awards and Honors:
    • Shield holder (Distinguished student) in Intermediate examination
    • Gold Medallist (Top student) + grant winner in Bachelor’s (Biology)
    • Grant’s winner (Top student, 6*3 months) in MSc Biochemistry
Peer Reviewer & Academic Engagements:
  1. Published Papers:
    • Contributed to multiple publications in high-impact journals such as European Journal of Pharmaceutical Sciences, Drug Metabolism and Disposition, Molecular Pharmaceutics, and International Journal of Pharmaceutics.
  2. Conference Abstract (2019):
    • Presented at Acta Ophthalmologica, contributing to the field of ocular carboxylesterases.
  3. Research Supervision:
    • Supervised two master’s thesis students, providing guidance and mentorship.

 

  • Aldehyde oxidase 1 activity and protein expression in human, rabbit, and pig ocular tissues
    • Journal: European Journal of Pharmaceutical Sciences
    • Date: 2023-12
    • DOI: 10.1016/j.ejps.2023.106603
  • Mass spectrometry in ocular drug research
    • Journal: Mass Spectrometry Reviews
    • Date: 2023-08-02
    • DOI: 10.1002/mas.21861
  • Activity and expression of carboxylesterases and arylacetamide deacetylase in human ocular tissues
    • Journal: Drug Metabolism and Disposition
    • Date: 2022-10-04
    • DOI: 10.1124/dmd.122.000993
  • Ocular metabolism and distribution of drugs in the rabbit eye: Quantitative assessment after intracameral and intravitreal administrations
    • Journal: International Journal of Pharmaceutics
    • Date: 2022-02
    • DOI: 10.1016/j.ijpharm.2021.121361
  • Carboxylesterase Activities and Protein Expression in Rabbit and Pig Ocular Tissues.
    • Journal: Molecular pharmaceutics
    • Date: 2021-02-17
    • PMID: 33595329
    • DOI: 10.1021/acs.molpharmaceut.0c01154
  • Characterization and tissue localization of ocular carboxylesterases in multiple species
    • Journal: Acta Ophthalmologica
    • Date: 2019-12
    • DOI: 10.1111/j.1755-3768.2019.5346
  • A Novel Heterozygous Intragenic Sequence Variant in DLX6 Probably Underlies First Case of Autosomal Dominant Split-Hand/Foot Malformation Type 1
    • Journal: Molecular Syndromology
    • Date: 2017
    • DOI: 10.1159/000453350