Felix Hausch | Drug Discovery | Best Researcher Award

Prof. Felix Hausch | Drug Discovery | Best Researcher AwardĀ 

Professor, Technische UniversitƤt Darmstadt, Germany

Professor Prof. Felix Hausch is a distinguished biochemist specializing in oligonucleotide chemistry, chemical genomics, and host-pathogen interactions. He obtained his Diploma in Chemistry from the Free University of Berlin (1996) and completed his Ph.D. in Biochemistry in 2000 under the mentorship of Prof. Dr. A. JƤschke. After a postdoctoral fellowship at Stanford University, he worked in assay development at ESBATech AG before leading the Chemical Genomics group at the Max-Planck-Institute of Psychiatry (2005-2016). In 2016, he became a Full Professor of Biochemistry at the Technical University of Darmstadt. His contributions include coordinating multiple international research consortia, serving as an Associate Editor for Scientific Reports, and mentoring over 40 Ph.D. students and postdoctoral researchers. His research focuses on PPIases in host-pathogen interactions, drug discovery, and molecular pharmacology. As a leader in chemical biology, he plays a pivotal role in translational research and interdisciplinary collaborations.

Professional ProfileĀ 

EducationĀ 

Diploma in Chemistry (1996) ā€“ Free University of Berlin, Germany Doctorate in Biochemistry (2000) ā€“ Free University of Berlin, under Prof. Dr. A. JƤschke, focusing on oligonucleotide chemistry. Postdoctoral Research (2000-2002) ā€“ Stanford University, Institute of Chemical Engineering, under Prof. Chaitan Khosla, studying biochemical engineering.Habilitation in Organic Chemistry & Biochemistry (2015) ā€“ Ludwig-Maximilians-University (LMU), Munich. Full Professor of Biochemistry (2016-Present) ā€“ Technical University Darmstadt, specializing in chemical biology, medicinal chemistry, and host-pathogen interactions.

ExperienceĀ 

Research Assistant (1996-2000) ā€“ Free University of Berlin, Biochemistry. Postdoctoral Fellow (2000-2002) ā€“ Stanford University, specializing in chemical engineering and enzyme function. Scientist in Assay Development (2002-2004) ā€“ ESBATech AG, Zurich, focusing on biochemical assay development. Group Leader, Chemical Genomics (2005-2016) ā€“ Max-Planck-Institute of Psychiatry, Munich, leading chemical biology and drug discovery projects.

Awards & Honors šŸ†

Coordinator of MSCA Doctoral Network MC4DD (2024-2028) ā€“ EU-funded research program. Speaker, LOEWE-Schwerpunkt TRABITA (2020-2024) ā€“ Advancing chemical biology and drug discovery. Vice Director, Clemens-Schƶpf-Institute (2019-Present) ā€“ Leading biochemical research collaborations. Chair of GDCh Local Section (2019-2022) ā€“ Strengthening chemical research networks.Coordinator of BMBF Consortia PROCERA, iMIP, SIAM-APH & 51TaValP, ProxiTRAPS, FamoGLUES ā€“ Leading international drug discovery projects

Research Focus šŸ”¬

Chemical Biology & Drug Discovery ā€“ Developing novel small-molecule inhibitors for protein targets. Ā Host-Pathogen Interactions ā€“ Investigating PPIases and their role in bacterial and viral infections.Ā Molecular Pharmacology ā€“ Understanding enzyme mechanisms and drug-target interactions. Ā Peptidyl-Prolyl Cis/Trans Isomerases (PPIases) ā€“ Studying their function in cellular signaling and infection control. Translational Research ā€“ Bridging the gap between fundamental biochemistry and clinical applications. Chemical Genomics ā€“ Using biochemical assays and structural biology to develop targeted therapies.

Conclusion

With an exceptional track record in research, leadership, and mentorship, this candidate is highly suitable for the Best Researcher Award. Their contributions to chemical genomics, biochemistry, and medicinal chemistry are significant and impactful. Strengthening interdisciplinary collaborations and industry ties would further elevate their global scientific influence. šŸš€

Publications Top Noted

šŸ“Œ Structural Insights into PPIase-Mediated Protein Folding and Drug Targeting
šŸ“Œ Development of Small-Molecule Inhibitors for Host-Pathogen Interactions
šŸ“Œ Chemical Genomics Strategies for Understanding Protein Function
šŸ“Œ Biochemical Assay Development for High-Throughput Drug Screening
šŸ“Œ Molecular Mechanisms of Enzyme Catalysis in Drug Discovery
šŸ“Œ Role of Peptidyl-Prolyl Cis/Trans Isomerases in Cellular Regulation
šŸ“Œ Host-Pathogen Interactions: The Role of PPIases in Bacterial Infections
šŸ“Œ Advances in Chemical Biology: New Strategies for Molecular Targeting
šŸ“Œ Enzyme Modulation for Therapeutic Applications in Infectious Diseases
šŸ“Œ Drug Discovery Approaches Using Chemical Genomics Techniques

Lianhua Bai | Immunology and liver diseases

šŸŒŸCongratulations on Receiving the Best Researcher Award! šŸŽ‰šŸ‘

  • Prof Dr. Lianhua Bai, Hepatobiliary Institute, Southwest Hospital, Army Medical University, China: Leading Researcher in Immunology and liver diseases

Dr. Lianhua Bai, Heartiest congratulations on being honored with the Best Researcher Award! šŸŒŸ by ScienceFather Your dedication, hard work, and outstanding contributions to the fields of Tumor Immunology, Cellular Immunology, Neuroimmunology, Stem Cells, and Regenerative Medicine have not only earned you this prestigious recognition but have also significantly enriched our understanding of these critical areas of research.

Your relentless pursuit of excellence and commitment to advancing scientific knowledge exemplify the true spirit of a visionary researcher. šŸš€ Your journey, from your early academic years to your current role as a Full Professor at the Hepatobiliary Institute, Southwest Hospital, Army Medical University, is a testament to your passion for making impactful contributions to the world of science.

May this award be a symbol of the profound impact your work has had on the scientific community, and may it inspire future generations of researchers to follow in your footsteps. Once again, heartfelt congratulations on this well-deserved achievement! šŸŽŠšŸ†

Professional Profiles:
Bio Summary:

Dr. Lianhua Bai is a distinguished researcher and educator with a diverse academic journey spanning Tumor Immunology, Cellular Immunology, Neuroimmunology, Stem Cells, and Regenerative Medicine. Currently a Full Professor at the Hepatobiliary Institute, Southwest Hospital, Army Medical University, her research focuses on advancing our understanding of hepatobiliary diseases. Dr. Bai has a notable publication record and has made significant contributions to the fields of immunology and regenerative medicine.

Education:
  • Bachelor’s Degree: Baotou Medical University, Inner Mongolia, China (Mar. 1978 ā€“ Dec. 1982)
  • M.D.: Anhui Medical University, Tumor Immunology research program, Hefei, Anhui province, China (Sept. 1986 – Sept.1989)
  • Ph.D.: Dalian Medical University, Tumor Immunology research program, Dalian, Liaoning province, China (Jul. 1992 ā€“ Sept. 1995)
Research Focus:
  • Initial focus on Tumor Immunology during M.D. and Ph.D. programs
  • Postdoctoral research in Cellular Immunology at the German Cancer Research Center (DKFZ), Heidelberg, Germany (Aug. 1998ā€“ Aug. 2001)
  • Shifted research focus to Neuroimmunology, Stem Cells, and Regenerative Medicine during the tenure at Case Western Reserve University, School of Medicine (Aug. 2001 ā€“ Nov. 2013)
  • Current emphasis on Hepatobiliary research as a Full Professor at the Hepatobiliary Institute, Southwest Hospital, Army Medical University, Chongqing, China (Nov. 2013 ā€“ Present)
Professional Journey:
  • Teaching Assistant, Department of Immunology and Microbiology, Baotou Medical University, Inner Mongolia, China (Dec. 1982 – Sept.1986)
  • Instructor, Department of Immunology and Microbiology, Baotou Medical University, Inner Mongolia, China (Sept. 1989 ā€“ Jul. 1992)
  • Associate Professor, Beijing University, Beijing, China (Sept. 1995 ā€“ Aug. 1998)
  • Postdoctoral Researcher, Department of Cellular Immunology, German Cancer Research Center (DKFZ), Heidelberg, Germany (Aug. 1998ā€“ Aug. 2001)
  • Instructor, Department of Neuroscience, Case Western Reserve University, School of Medicine, Cleveland Hts OH, U.S.A (Aug. 2001 ā€“ Nov. 2013)
  • Full Professor, Hepatobiliary Institute, Southwest Hospital, Army Medical University, Chongqing, China (Nov. 2013 ā€“ Present)
Research Timeline:
  1. Tumor Immunology Research (Baotou Medical University, Anhui Medical University, Dalian Medical University)
  2. Cellular Immunology Research (German Cancer Research Center, Heidelberg, Germany)
  3. Neuroimmunology, Stem Cells, and Regenerative Medicine Research (Case Western Reserve University, School of Medicine)
  4. Hepatobiliary Research (Hepatobiliary Institute, Southwest Hospital, Army Medical University)
Publications Top Noted:
  1. Hepatocyte growth factor-mediated apoptosis mechanisms of cytotoxic CD8+ T cells in normal and cirrhotic livers
    • Authors: Chen, Q., Yan, M., Lin, H., …, Zhang, H., Bai, L.
    • Journal: Cell Death Discovery, 2023
    • Citations: 2
  2. Comparative effects of hepatocyte growth factor and tacrolimus on acute liver allograft early tolerance
    • Authors: Chen, Q., Yang, Z., Lin, H., …, Zhang, L., Bai, L.
    • Journal: Frontiers in Immunology, 2023
    • Citations: 0
  3. Immunotherapeutic Targeting of NG2/CSPG4 in Solid Organ Cancers
    • Authors: Zhang, H., Wu, Z., Hu, D., …, Lai, J., Bai, L.
    • Journal: Vaccines, 2022
    • Citations: 1
  4. Comparison of the biological and functional characteristics of mesenchymal stem cells from intrahepatic and identical bone marrow
    • Authors: Lai, J., Jiang, S., Shuai, L., …, Chen, Q., Bai, L.
    • Journal: Stem Cell Research, 2021
    • Citations: 3
  5. Hepatocyte growth factor mediates a novel form of hepatic stem/progenitor cell-induced tolerance in a rat xenogeneic liver rejection model
    • Authors: Chen, Q., You, Y., Zhang, Y., …, Zhang, H., Bai, L.
    • Journal: International Immunopharmacology, 2021
    • Citations: 5
  6. Future in regenerative surgical discipline: construction engineered liver with optimized strategy of decellularized and recellularized technology
    • Authors: Zhang, L., Xia, R., Zhang, Y., …, Zhang, H., Bai, L.
    • Journal: Chinese Journal of Digestive Surgery, 2020
    • Citations: 0
  7. Survival of endogenous hepatic stem/progenitor cells in liver tissues during liver cirrhosis
    • Authors: Chen, Q., You, X., Yang, W., …, Zhang, H., Bai, L.
    • Journal: Life Sciences, 2020
    • Citations: 13
  8. Research progress on immunosuppressants and new drugs for liver transplantation
    • Authors: Chen, Q., Jiang, S., Xia, R., …, Zhang, H., Bai, L.
    • Journal: Organ Transplantation, 2020
    • Citations: 2
  9. Data on a novel liver bioscaffold (rDLS) generated from regenerative liver with activated extracellular matrix for functional liver regeneration
    • Authors: Yang, W., Chen, Q., Bai, L.
    • Journal: Data in Brief, 2019
    • Citations: 1
  10. A novel bioscaffold with naturally-occurring extracellular matrix promotes hepatocyte survival and vessel patency in mouse models of heterologous transplantation
    • Authors: Yang, W., Chen, Q., Xia, R., …, Zhang, H., Bai, L.
    • Journal: Biomaterials, 2018
    • Citations: 17