Guohai Zhang | Medicinal Chemistry | Best Researcher Award

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🌟Dr. Guohai Zhang, Medicinal Chemistry, Young Scientist Award🏆

Doctorate at Guangxi Normal University, China

Guo-Hai Zhang is an Associate Professor at the State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, Guangxi Normal University. His research primarily focuses on targeted therapy and drug resistance mechanisms in lung cancer. He has made significant contributions to understanding the role of wild-type EGFR and p53 in non-small cell lung cancer (NSCLC), as well as the molecular basis of p53 mitochondrial localization. Guo-Hai Zhang has conducted numerous research projects funded by the National Natural Science Foundation of China (NSFC) and Guangxi NSFC, resulting in 20 SCI papers published in reputable journals.

Author Metrics

Scopus Profile

Guo-Hai Zhang has authored or co-authored 20 SCI papers published in journals such as J Med Chem, J Biol Chem, Biochem Pharmacol, and Eur J Med Chem. These publications demonstrate his impact and recognition in the field of lung cancer research, particularly in understanding targeted therapy and drug resistance mechanisms.

Citations: 566 citations by 514 documents

Documents: 27

h-index: 14

Education

Guo-Hai Zhang pursued his Ph.D. in the medical field at Nanjing University. Prior to that, he obtained a Master’s degree from Huaqiao University and a Bachelor’s degree from Shandong University of Science and Technology, both focusing on molecular medicine and chemistry.

Research Focus

Guo-Hai Zhang’s research primarily focuses on targeted therapy and drug resistance mechanisms in lung cancer, particularly non-small cell lung cancer (NSCLC). His work includes elucidating the role of wild-type EGFR and p53 in NSCLC, understanding the molecular mechanisms underlying drug resistance, and exploring intervention methods to overcome resistance.

Professional Journey

Guo-Hai Zhang’s professional journey began as a Research Associate at the State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, Guangxi Normal University, where he conducted research from 2011 to 2017. Since December 2017, he has held the position of Associate Professor at the same institution, continuing his research in targeted therapy and drug resistance mechanisms in lung cancer.

Honors & Awards

Guo-Hai Zhang’s contributions to the field of lung cancer research have earned him recognition and honors, although specific awards and honors are not mentioned in the provided information.

Publications Noted & Contributions

Guo-Hai Zhang has made notable contributions to the field of lung cancer research through his publications. Some of his key contributions include elucidating the role of wild-type EGFR and p53 in NSCLC, understanding the molecular mechanisms of drug resistance, and exploring intervention methods to overcome resistance. His research findings have been published in reputable journals such as J Med Chem, J Biol Chem, Biochem Pharmacol, and Eur J Med Chem.

Title: Small-molecule MX-C2/3 suppresses non-small cell lung cancer progression via p53 activation
Authors: Li, L., Du, W., Wang, H., …, Zeng, S., Zhang, G.
Journal: Chemico-Biological Interactions, 2022, 366, 110142
Citations: 1

Title: Therapeutic restoring p53 function with small molecule for oncogene-driven non-small cell lung cancer by targeting serine 392 phosphorylation
Authors: Li, L., Li, P., Ma, X., …, Peng, Y., Zhang, G.
Journal: Biochemical Pharmacology, 2022, 203, 115188
Citations: 3

Title: Axl Mediates Resistance to Respiratory Syncytial Virus Infection Independent of Cell Attachment
Authors: Zhang, D., Zhao, Y., Wang, L., …, He, S., Li, E.
Journal: American Journal of Respiratory Cell and Molecular Biology, 2022, 67(2), pp. 227–240
Citations: 1

Title: Targeting entry into mitochondria for increased anticancer efficacy of BCL-XL-selective inhibitors in lung cancer
Authors: Li, L., Li, P., Song, H., …, Peng, Y., Zhang, G.
Journal: Pharmacological Research, 2022, 177, 106095
Citations: 2

Title: Glycyrrhizic acid inhibits SARS-CoV-2 infection by blocking spike protein-mediated cell attachment
Authors: Li, J., Xu, D., Wang, L., …, Li, E., He, S.
Journal: Molecules, 2021, 26(20), 6090
Citations: 32

Research Timeline

Guo-Hai Zhang’s research timeline spans from his tenure as a Research Associate from 2011 to 2017 to his current position as an Associate Professor, which he has held since December 2017. Throughout this time, he has been actively involved in conducting research projects funded by the National Natural Science Foundation of China (NSFC) and Guangxi NSFC.

Collaborations and Projects

Guo-Hai Zhang has collaborated on various research projects focused on targeted therapy and drug resistance mechanisms in lung cancer. His research group has conducted projects funded by the National Natural Science Foundation of China (NSFC) and Guangxi NSFC, contributing to the understanding of lung cancer biology and the development of targeted therapies.

Febee Louka | Medicinal Chemistry | Best Researcher Award

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🌟Prof. Febee Louka, Medicinal Chemistry, Best Researcher Award 🏆

  •  Professor at University of Louisiana at Lafayette, United States

Febee R. Y. Louka is a distinguished Professor of Chemistry at the University of Louisiana at Lafayette (ULL). With a Ph.D. in Analytical/Medicinal Chemistry from Ohio University, she has established herself as a leading figure in the field. Her expertise spans various areas, including synthesizing complex metal complexes, monitoring environmental pollution, and developing novel biosensors. Dr. Louka’s commitment to research, teaching, and service has earned her numerous accolades and positions of leadership within academia.

Author Metrics

Scopus Profile

ORCID Profile

Dr. Louka’s contributions to scientific literature are substantial, with a prolific publication record and significant citations. Her work has been recognized for its impact on the field, as evidenced by her author metrics, including citation count, h-index, and publication output across prestigious journals.

Citations: Febee R. Y. Louka has received a total of 1,267 citations across 929 documents.

Documents: She has authored 54 documents indexed in Scopus.

h-index: The h-index is 22, indicating that Febee R. Y. Louka has published at least 22 papers that have each been cited at least 22 times.

Education

Febee Louka holds a Ph.D. in Analytical/Medicinal Chemistry from Ohio University, complemented by an M.Sc. and B.Sc. in Chemistry from Alexandria University, Egypt. Her academic journey has equipped her with a strong foundation in both theoretical knowledge and practical laboratory skills, enabling her to pursue cutting-edge research in her field.

Research Focus

Dr. Louka’s research focuses on several key areas, including the synthesis and characterization of metal complexes with potential applications in medicine and environmental remediation. She is also deeply involved in the development of biosensors for detecting pollutants and monitoring biological processes. Her interdisciplinary approach integrates chemistry, biology, and environmental science to address complex scientific challenges.

Professional Journey

Febee Louka’s professional journey encompasses a diverse range of roles, from teaching assistantships to tenure-track professorships. With positions at both Ohio University and ULL, she has demonstrated a commitment to education and research excellence. Her career progression reflects her dedication to advancing knowledge and fostering the next generation of scientists.

Honors & Awards

Throughout her career, Dr. Louka has received numerous honors and awards for her outstanding contributions to academia. These accolades recognize her excellence in teaching, research, and service, as well as her leadership within the university community. Her sustained impact and recognition highlight her significant contributions to the field of chemistry.

Publications Noted & Contributions

Dr. Louka’s publications are noteworthy for their scientific rigor and innovative contributions to the field. Her research papers have appeared in leading journals and have been cited extensively by peers. Additionally, she has contributed to the advancement of scientific knowledge through her mentorship of students and participation in collaborative research projects.

Title: “Copper(II) and zinc(II) complexes bridged by benzenoid aromatic oxocarbon and dicarboxylate dianions”

Authors: Mautner, F.A., Fischer, R.C., Torvisco, A., Louka, F.R., Massoud, S.S.

Journal: Polyhedron, 2023, 234, 116327

Title: “Magnetostructural Properties of Some Doubly-Bridged Phenoxido Copper(II) Complexes”

Authors: Massoud, S.S., Louka, F.R., Dial, M.T., Handa, M., Mikuriya, M.

Journal: Molecules, 2023, 28(6), 2648

Title: “Dinuclear doubly bridged phenoxido copper(II) complexes as efficient anticancer agents”

Authors: Massoud, S.S., Louka, F.R., Salem, N.M.H., Dvořák, Z., Trávníček, Z.

Journal: European Journal of Medicinal Chemistry, 2023, 246, 114992

Title: “Miscellaneous dimensional coordination polymers and luminescence emission properties of cadmium(II)-pseudohalide complexes”

Authors: Mautner, F.A., Fischer, R.C., Salem, N.M.H., Louka, F.R., Massoud, S.S.

Journal: Inorganica Chimica Acta, 2022, 535, 120871

Title: “Identification of potent anticancer copper(ii) complexes containing tripodal bis[2-ethyl-di(3,5-dialkyl-1H-pyrazol-1-yl)]amine moiety”

Authors: Massoud, S.S., Louka, F.R., Dial, M.T., Dvořák, Z., Trávníček, Z.

Journal: Dalton Transactions, 2021, 50(33), pp. 11521–11534

Research Timeline

Febee Louka’s research timeline illustrates her evolution as a scientist and the progression of her research interests over time. From her early work on metal complex synthesis to her current focus on environmental monitoring and biosensor development, her research trajectory reflects a commitment to addressing pressing societal and scientific challenges.

Collaborations and Projects

Dr. Louka has engaged in numerous collaborative projects with researchers from diverse backgrounds. These collaborations have led to interdisciplinary breakthroughs and innovative solutions to complex problems. By working across disciplines, she has expanded the scope of her research and fostered fruitful partnerships within and beyond academia.