Guohai Zhang | Medicinal Chemistry | Best Researcher Award

🌟Dr. Guohai Zhang, Medicinal Chemistry, Young Scientist AwardπŸ†

Doctorate at Guangxi Normal University, China

Guo-Hai Zhang is an Associate Professor at the State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, Guangxi Normal University. His research primarily focuses on targeted therapy and drug resistance mechanisms in lung cancer. He has made significant contributions to understanding the role of wild-type EGFR and p53 in non-small cell lung cancer (NSCLC), as well as the molecular basis of p53 mitochondrial localization. Guo-Hai Zhang has conducted numerous research projects funded by the National Natural Science Foundation of China (NSFC) and Guangxi NSFC, resulting in 20 SCI papers published in reputable journals.

Author Metrics

Scopus Profile

Guo-Hai Zhang has authored or co-authored 20 SCI papers published in journals such as J Med Chem, J Biol Chem, Biochem Pharmacol, and Eur J Med Chem. These publications demonstrate his impact and recognition in the field of lung cancer research, particularly in understanding targeted therapy and drug resistance mechanisms.

Citations: 566 citations by 514 documents

Documents: 27

h-index: 14

Education

Guo-Hai Zhang pursued his Ph.D. in the medical field at Nanjing University. Prior to that, he obtained a Master’s degree from Huaqiao University and a Bachelor’s degree from Shandong University of Science and Technology, both focusing on molecular medicine and chemistry.

Research Focus

Guo-Hai Zhang’s research primarily focuses on targeted therapy and drug resistance mechanisms in lung cancer, particularly non-small cell lung cancer (NSCLC). His work includes elucidating the role of wild-type EGFR and p53 in NSCLC, understanding the molecular mechanisms underlying drug resistance, and exploring intervention methods to overcome resistance.

Professional Journey

Guo-Hai Zhang’s professional journey began as a Research Associate at the State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, Guangxi Normal University, where he conducted research from 2011 to 2017. Since December 2017, he has held the position of Associate Professor at the same institution, continuing his research in targeted therapy and drug resistance mechanisms in lung cancer.

Honors & Awards

Guo-Hai Zhang’s contributions to the field of lung cancer research have earned him recognition and honors, although specific awards and honors are not mentioned in the provided information.

Publications Noted & Contributions

Guo-Hai Zhang has made notable contributions to the field of lung cancer research through his publications. Some of his key contributions include elucidating the role of wild-type EGFR and p53 in NSCLC, understanding the molecular mechanisms of drug resistance, and exploring intervention methods to overcome resistance. His research findings have been published in reputable journals such as J Med Chem, J Biol Chem, Biochem Pharmacol, and Eur J Med Chem.

Title: Small-molecule MX-C2/3 suppresses non-small cell lung cancer progression via p53 activation
Authors: Li, L., Du, W., Wang, H., …, Zeng, S., Zhang, G.
Journal: Chemico-Biological Interactions, 2022, 366, 110142
Citations: 1

Title: Therapeutic restoring p53 function with small molecule for oncogene-driven non-small cell lung cancer by targeting serine 392 phosphorylation
Authors: Li, L., Li, P., Ma, X., …, Peng, Y., Zhang, G.
Journal: Biochemical Pharmacology, 2022, 203, 115188
Citations: 3

Title: Axl Mediates Resistance to Respiratory Syncytial Virus Infection Independent of Cell Attachment
Authors: Zhang, D., Zhao, Y., Wang, L., …, He, S., Li, E.
Journal: American Journal of Respiratory Cell and Molecular Biology, 2022, 67(2), pp. 227–240
Citations: 1

Title: Targeting entry into mitochondria for increased anticancer efficacy of BCL-XL-selective inhibitors in lung cancer
Authors: Li, L., Li, P., Song, H., …, Peng, Y., Zhang, G.
Journal: Pharmacological Research, 2022, 177, 106095
Citations: 2

Title: Glycyrrhizic acid inhibits SARS-CoV-2 infection by blocking spike protein-mediated cell attachment
Authors: Li, J., Xu, D., Wang, L., …, Li, E., He, S.
Journal: Molecules, 2021, 26(20), 6090
Citations: 32

Research Timeline

Guo-Hai Zhang’s research timeline spans from his tenure as a Research Associate from 2011 to 2017 to his current position as an Associate Professor, which he has held since December 2017. Throughout this time, he has been actively involved in conducting research projects funded by the National Natural Science Foundation of China (NSFC) and Guangxi NSFC.

Collaborations and Projects

Guo-Hai Zhang has collaborated on various research projects focused on targeted therapy and drug resistance mechanisms in lung cancer. His research group has conducted projects funded by the National Natural Science Foundation of China (NSFC) and Guangxi NSFC, contributing to the understanding of lung cancer biology and the development of targeted therapies.

Yiran Li | Pharmacokinetics | Young Scientist Award

🌟Dr. Yiran Li, Pharmacokinetics, Young Scientist AwardπŸ†

Doctorate at Nanjing University of Aeronautics and Astronautics, China

Li Yiran, born on December 1, 1992, in Jilin, Jilin Province, China, is a dedicated researcher in the field of pharmacokinetics and biomedical instrumentation. As a member of the Communist Party of China, they hold a strong commitment to scientific progress and innovation. With a Ph.D. from Nanjing University of Aeronautics and Astronautics, Li Yiran has demonstrated exceptional leadership and expertise in managing research projects and teams. Their contributions to academia include numerous publications in esteemed journals and presentations at international conferences.

Author Metrics:

Scopus Profile

Li Yiran’s academic achievements are underscored by their author metrics, which include publications in high-impact journals such as Molecular Imaging and Biology and Biomedical Optics Express. They have also presented their research findings at various international conferences, contributing to the dissemination of knowledge in their field.

Li Yiran’s publications have been cited 6 times across 5 documents, indicating a modest but notable impact within their field. The h-index, which measures both the productivity and impact of an author’s publications, is currently not available in the provided information.

Education:

Li Yiran’s academic journey began with a Bachelor’s degree in Biomedical Engineering from Changchun University of Science and Technology. They continued their studies with a Master’s degree in Biomedical Image Processing from the same institution. Currently pursuing a Ph.D. in Instrument Science and Technology at Nanjing University of Aeronautics and Astronautics, Li Yiran’s educational background reflects their dedication to interdisciplinary research in biomedical instrumentation and pharmacokinetics.

Research Focus:

Li Yiran’s research focuses primarily on pharmacokinetics research and instrument development. Their work involves the design and implementation of innovative monitoring systems for studying drug metabolism and transport dynamics in living organisms, particularly small animals. This research contributes to advancements in drug delivery systems and therapeutic interventions.

Professional Journey:

Throughout their professional journey, Li Yiran has demonstrated exceptional skills in project management, instrument development, academic writing, and public speaking. They have led research teams and collaborated with peers and supervisors to address complex challenges in pharmacokinetics and biomedical instrumentation. Their dedication to research excellence has earned them recognition and awards at various levels.

Honors & Awards:

Li Yiran’s outstanding contributions to research and innovation have been recognized through numerous honors and awards. These accolades include prestigious national awards, provincial and ministerial level recognition, municipal awards, and paper awards. Their achievements underscore their commitment to academic excellence and leadership in their field.

Publications Noted & Contributions:

Li Yiran’s publications in reputable journals such as Molecular Imaging and Biology and Biomedical Optics Express highlight their significant contributions to the field of pharmacokinetics and biomedical instrumentation. Their research findings provide valuable insights into drug metabolism, transport dynamics, and the development of monitoring systems for in vivo studies.

Multi-channel Small Animal Drug Metabolism Real-Time Monitoring Fluorescence System

Authors: Li, Y., Jin, X., Wang, F., …, Qian, Z., Li, W.

Published in: Molecular Imaging and Biology, 2024, 26(1), pp. 138–147

Abstract: This article presents a multi-channel small animal drug metabolism real-time monitoring fluorescence system. Unfortunately, the abstract is not available.

Evaluation method of ex vivo porcine liver reduced scattering coefficient during microwave ablation based on temperature

Authors: Jin, X., Liu, W., Li, Y., …, Li, W., Qian, Z.

Published in: Biomedizinische Technik, 2022, 67(6), pp. 491–501

Abstract: This article describes an evaluation method of ex vivo porcine liver reduced scattering coefficient during microwave ablation based on temperature. Unfortunately, the abstract is not available.

Real-time evaluation of microwave ablation based on the combination of near-infrared spectroscopy technology and shear wave elastography technology

Authors: Jin, X., Li, Y., Feng, Y., …, Qian, Z., Zhou, J.

Published in: Proceedings of SPIE – The International Society for Optical Engineering, 2021, 11900, 119002S

Abstract: This article discusses the real-time evaluation of microwave ablation based on the combination of near-infrared spectroscopy technology and shear wave elastography technology. Unfortunately, the abstract is not available.

Study on the relationship between reduced scattering coefficient and Young’s modulus of tumors in microwave ablation

Authors: Jin, X., Li, Y., Liu, W., …, Li, W., Zhou, J.

Published in: Minimally Invasive Therapy and Allied Technologies, 2021, 30(6), pp. 347–355

Abstract: This article presents a study on the relationship between the reduced scattering coefficient and Young’s modulus of tumors in microwave ablation. Unfortunately, the abstract is not available.

Study of cervical precancerous lesions detection by spectroscopy and support vector machine

Authors: Liu, W., Jin, X., Li, J., …, Li, W., Yan, X.

Published in: Minimally Invasive Therapy and Allied Technologies, 2021, 30(4), pp. 208–214

Abstract: This article presents a study of cervical precancerous lesions detection by spectroscopy and support vector machine. Unfortunately, the abstract is not available.

Research Timeline:

Li Yiran’s research journey spans from their undergraduate studies to their current Ph.D. pursuit. They have been involved in various research projects, including the development of precision microwave thermal ablation equipment for tumor treatment and the design of multi-scale imaging systems for studying nanomedicine transport characteristics. Their research timeline reflects a continuous dedication to advancing scientific knowledge and technological innovation.

Collaborations and Projects:

Li Yiran has collaborated with peers, supervisors, and research teams on multiple projects, both within academic institutions and through external funding sources. Their involvement in projects such as the National Natural Science Foundation of China’s major scientific research instrument development project demonstrates their ability to work effectively in multidisciplinary teams and contribute to impactful research initiatives.