Felix Hausch | Drug Discovery | Best Researcher Award

Prof. Felix Hausch | Drug Discovery | Best Researcher Award 

Professor, Technische Universität Darmstadt, Germany

Professor Prof. Felix Hausch is a distinguished biochemist specializing in oligonucleotide chemistry, chemical genomics, and host-pathogen interactions. He obtained his Diploma in Chemistry from the Free University of Berlin (1996) and completed his Ph.D. in Biochemistry in 2000 under the mentorship of Prof. Dr. A. Jäschke. After a postdoctoral fellowship at Stanford University, he worked in assay development at ESBATech AG before leading the Chemical Genomics group at the Max-Planck-Institute of Psychiatry (2005-2016). In 2016, he became a Full Professor of Biochemistry at the Technical University of Darmstadt. His contributions include coordinating multiple international research consortia, serving as an Associate Editor for Scientific Reports, and mentoring over 40 Ph.D. students and postdoctoral researchers. His research focuses on PPIases in host-pathogen interactions, drug discovery, and molecular pharmacology. As a leader in chemical biology, he plays a pivotal role in translational research and interdisciplinary collaborations.

Professional Profile 

Education 

Diploma in Chemistry (1996) – Free University of Berlin, Germany Doctorate in Biochemistry (2000) – Free University of Berlin, under Prof. Dr. A. Jäschke, focusing on oligonucleotide chemistry. Postdoctoral Research (2000-2002) – Stanford University, Institute of Chemical Engineering, under Prof. Chaitan Khosla, studying biochemical engineering.Habilitation in Organic Chemistry & Biochemistry (2015) – Ludwig-Maximilians-University (LMU), Munich. Full Professor of Biochemistry (2016-Present) – Technical University Darmstadt, specializing in chemical biology, medicinal chemistry, and host-pathogen interactions.

Experience 

Research Assistant (1996-2000) – Free University of Berlin, Biochemistry. Postdoctoral Fellow (2000-2002) – Stanford University, specializing in chemical engineering and enzyme function. Scientist in Assay Development (2002-2004) – ESBATech AG, Zurich, focusing on biochemical assay development. Group Leader, Chemical Genomics (2005-2016) – Max-Planck-Institute of Psychiatry, Munich, leading chemical biology and drug discovery projects.

Awards & Honors 🏆

Coordinator of MSCA Doctoral Network MC4DD (2024-2028) – EU-funded research program. Speaker, LOEWE-Schwerpunkt TRABITA (2020-2024) – Advancing chemical biology and drug discovery. Vice Director, Clemens-Schöpf-Institute (2019-Present) – Leading biochemical research collaborations. Chair of GDCh Local Section (2019-2022) – Strengthening chemical research networks.Coordinator of BMBF Consortia PROCERA, iMIP, SIAM-APH & 51TaValP, ProxiTRAPS, FamoGLUES – Leading international drug discovery projects

Research Focus 🔬

Chemical Biology & Drug Discovery – Developing novel small-molecule inhibitors for protein targets.  Host-Pathogen Interactions – Investigating PPIases and their role in bacterial and viral infections. Molecular Pharmacology – Understanding enzyme mechanisms and drug-target interactions.  Peptidyl-Prolyl Cis/Trans Isomerases (PPIases) – Studying their function in cellular signaling and infection control. Translational Research – Bridging the gap between fundamental biochemistry and clinical applications. Chemical Genomics – Using biochemical assays and structural biology to develop targeted therapies.

Conclusion

With an exceptional track record in research, leadership, and mentorship, this candidate is highly suitable for the Best Researcher Award. Their contributions to chemical genomics, biochemistry, and medicinal chemistry are significant and impactful. Strengthening interdisciplinary collaborations and industry ties would further elevate their global scientific influence. 🚀

Publications Top Noted

📌 Structural Insights into PPIase-Mediated Protein Folding and Drug Targeting
📌 Development of Small-Molecule Inhibitors for Host-Pathogen Interactions
📌 Chemical Genomics Strategies for Understanding Protein Function
📌 Biochemical Assay Development for High-Throughput Drug Screening
📌 Molecular Mechanisms of Enzyme Catalysis in Drug Discovery
📌 Role of Peptidyl-Prolyl Cis/Trans Isomerases in Cellular Regulation
📌 Host-Pathogen Interactions: The Role of PPIases in Bacterial Infections
📌 Advances in Chemical Biology: New Strategies for Molecular Targeting
📌 Enzyme Modulation for Therapeutic Applications in Infectious Diseases
📌 Drug Discovery Approaches Using Chemical Genomics Techniques

Prof Kanghong Hu | Antiviral drugs | Best Researcher Award Winner 2023 | 23101

🎉🏆 Congratulations, Prof. Dr. Kanghong HU, on Your Outstanding Achievement as the Best Researcher! 🏆🎉

Prof. Kanghong Hu: Leading Researcher in Antiviral drugs

Your relentless dedication to the field of Molecular Virology and your groundbreaking contributions to Viral RNA Structure/Function Relationships have set a new standard for excellence in scientific research. Your innovative projects spanning over 35 years, from deciphering viroid replication to unraveling the intricacies of HBV, showcase not only your expertise but also your unwavering commitment to advancing scientific knowledge.

Your leadership as the Director of the Sino-German Biomedical Center at Hubei University of Technology has been instrumental in fostering collaborative research and pushing the boundaries of biomedical science. Your numerous awards, including the Friedrich Ebert Foundation Fellowship and the 2nd Prize of Scientific and Technological Progress, are a testament to your exceptional achievements and the impact of your work.

We applaud your remarkable journey, marked by significant achievements, cutting-edge research, and a passion for unraveling the mysteries of virology. Your selection as the Best Researcher is a well-deserved honor, reflecting the admiration and recognition of your peers and the broader scientific community.

May your future endeavors continue to inspire, innovate, and contribute to the advancement of knowledge in virology and beyond. Congratulations once again on this prestigious recognition—your legacy in scientific exploration shines brightly!

👨‍🔬 Prof. Dr. Kanghong HU

Professional Profiles:

Education:

  • 2000: Dr. Kanghong HU,(magna cum laude) Molecular Virology, University of Düsseldorf, Germany
    Supervisor: Prof. Dr. Detlev Riesner, Director
  • 1988: Master of Science, Molecular Virology, Wuhan Institute of Virology, Chinese Academy of Sciences (CAS), China
    Supervisor: Prof. Dr. Daming Ding, Director
  • 1985: Bachelor of Science, Microbiology, Wuhan University, China

Research Experiences:

  • 2014.01-Present: Director, Sino-German Biomedical Center, Hubei University of Technology
  • 2008.03-2013.12: Professor, Principal Investigator, Wuhan Institute of Virology, Chinese Academy of Sciences
  • 2006.04-2008.02: Senior Scientist, University of Regensburg, Institute of Molecular and Cellular Anatomy
  • 2003.03-2006.03: Senior Scientist, University Hospital of Regensburg, Department of Internal Medicine I
  • 2000.09-2003.02: Postdoc Fellow, University Hospital of Freiburg, Department of Internal Medicine II
  • 2000.03-2000.08: Postdoc Fellow, University of Duesseldorf, Institute of Physical Biology
  • 1995.12-2000.02: PhD Candidate, University of Duesseldorf, Institute of Physical Biology
  • 1988.08-1995.11: Research Assistant (1988) and Research Associate (1990), Wuhan Institute of Virology, CAS, Wuhan, China

Research Projects in the Last 35 Years:

  • Cloning and expression of the human growth hormone-releasing factor gene
  • Biochemical analysis of citrus exocortis viroid
  • Viroid replication and pathogenesis
  • In vitro selection of duck Hepatitis B virus epsilon variants
  • Mechanism of liver fibrosis
  • Basic aspects towards developmental biology of kidneys and livers
  • HBV replication and virus-host interaction
  • Study of the replication of hepatitis B virus
  • In vitro screening of anti-HBV decoys using SELEX technology
  • Establishment of a novel perfused 3D cell culture technique
  • Preclinical study of anti-HBV decoys
  • Directed differentiation technology system for pancreatic islets derived from pluripotent stem cells

Honors and Awards:

  • Excellent graduate of Wuhan University in 1985
  • 2nd Award for Excellent Papers in Science & Technology Association, China, 1990
  • Friedrich Ebert Foundation Fellowship, Germany (1995-1997)
  • Editorial Board Member: “Pathogen & Infectious Diseases,” “Virology & Retrovirology”
  • “The Industrial Recognized 3-Dimensional Cell Culture International Expert,” San Diego, USA
  • 2nd Prize of Scientific and Technological Progress of Chinese Preventive Medicine Association

Authorized Invention Patents:

  1. Container for three-dimensional perfusion cell culture
  2. Anti-HBV aptamer and its screening method
  3. Method of siRNA mediated by lentiviral vectors
  4. Co-culture technique of human primary hepatocytes and hepatic non-parenchymal cells
  5. Container for three-dimensional perfusion cell culture and its application
  6. Enzyme label cleaner
  7. Suture-free medical zipper for deep contusion and laceration
  8. Application of (E)-3-(benzo[d][1,3]dioxol-5-ylmethylene)-2-oxopyrrolidine-1-carbaldehyde in the preparation of chemicals against hepatitis B virus
  9. Simple pipetting head device for batch transfer and packaging

🔬 Research Focus:

  • Molecular Virology
  • Viral RNA Structure/Function Relationship
  • Liver Fibrosis
  • Developmental Biology of Kidneys and Livers
  • HBV Replication and Virus-Host Interaction
  • 3D Cell Culture Techniques
  • Pancreatic Islet Differentiation from Pluripotent Stem Cells