Professor at Noorda College of Osteopathic Medicine, United States
Dr. Kota V. Ramana is a Professor in the Department of Biomedical Sciences at Noorda College of Osteopathic Medicine, Provo, UT, USA. He specializes in cellular metabolism, oxidative stress, and inflammation, focusing on the role of aldo-keto reductases in inflammatory pathways. His research aims to understand how cellular metabolites regulate inflammatory responses in various diseases such as diabetes, sepsis, uveitis, asthma, and cancer. Dr. Ramana employs diverse genetic, biochemical, and cell biological techniques to explore the underlying mechanisms of inflammation and develop therapeutic strategies. He has made significant contributions to the understanding of oxidative stress signaling, cell death pathways, and polyol pathway enzymes in inflammatory conditions, with numerous publications in prestigious journals.
Professional Profile
Education
Dr. Kota V. Ramana holds a Ph.D. in Biochemistry from the Postgraduate Institute of Medical Education and Research in India. His academic foundation laid the groundwork for his research into cellular metabolism and oxidative stress. This rigorous training has enabled him to delve into the biochemical pathways involved in inflammatory diseases, equipping him with a deep understanding of the complex biological systems at play. His educational background continues to shape his approach to studying inflammation and metabolic regulation in disease contexts, forming the basis for his current investigations and innovations in biomedical research.
Professional Experience
Dr. Kota V. Ramana currently serves as a Professor at Noorda College of Osteopathic Medicine, where he leads research on cellular metabolism and inflammation. Over the years, he has gained substantial experience in various aspects of biochemistry, including cell biology and genetic analysis. His work spans multiple inflammatory diseases, aiming to develop novel therapeutic approaches. Additionally, he has contributed to numerous journal articles on oxidative stress, cell signaling, and the role of enzymes in diseases. His academic and research roles have positioned him as a leader in his field, fostering collaborations and advancing scientific understanding of inflammation-related pathologies.
Research Interest
Dr. Kota V. Ramana’s research interests are primarily focused on understanding the molecular mechanisms that govern cellular metabolism, oxidative stress, and inflammation. His work aims to explore the role of aldo-keto reductases in the regulation of inflammatory pathways. He is particularly interested in how cellular metabolites influence signal transduction, cell death, and survival during inflammatory responses. His research addresses a wide range of inflammatory diseases, including diabetes, sepsis, uveitis, asthma, and cancer. By using genetic, biochemical, and cell biological techniques, Dr. Ramana seeks to develop therapeutic strategies that target oxidative stress and metabolic disturbances associated with these pathologies. His interdisciplinary approach to understanding cellular processes at the molecular level holds promise for advancing treatments for inflammatory and metabolic disorders.
Awards and Honors
Dr. Kota V. Ramana has earned recognition for his significant contributions to biomedical research, particularly in the areas of inflammation, oxidative stress, and cellular metabolism. Although specific awards and honors are not detailed, his academic achievements include numerous publications in prestigious peer-reviewed journals, such as the International Journal of Molecular Sciences, Current Molecular Medicine, and Future Medicinal Chemistry. These accolades highlight his excellence in research and his role as a thought leader in his field. His continued efforts to innovate therapeutic strategies for inflammation-related diseases demonstrate his commitment to advancing medical science and improving patient outcomes. Dr. Ramana’s reputation for high-quality research has led to collaborations with leading experts, further solidifying his position as a prominent figure in biochemistry and biomedical sciences.
Publications Top Noted
- Therapeutic Significance of NLRP3 Inflammasome in Cancer: Friend or Foe?
- Authors: Jalali, A.M., Mitchell, K.J., Pompoco, C., Tran, S., Ramana, K.V.
- Year: 2024
- Citations: 0
- Anti-Inflammatory Potential of the Anti-Diabetic Drug Metformin in the Prevention of Inflammatory Complications and Infectious Diseases Including COVID-19: A Narrative Review
- Authors: Plowman, T.J., Christensen, H., Aiges, M., Shah, M.H., Ramana, K.V.
- Year: 2024
- Citations: 5
- Significance of Vitamin Supplementation in Reducing the Severity of COVID-19
- Authors: Aiges, M., Ramana, K.V.
- Year: 2024
- Citations: 0
- Role of Innate Immune and Inflammatory Responses in the Development of Secondary Diabetic Complications
- Authors: Plowman, T.J., Shah, M.H., Fernandez, E., Aiges, M., Ramana, K.V.
- Year: 2023
- Citations: 7
- Therapeutic Potential of Vitamin B1 Derivative Benfotiamine from Diabetes to COVID-19
- Authors: Allowitz, K.V., Yoo, J.J., Taylor, J.R., Harames, K., Ramana, K.V.
- Year: 2022
- Citations: 2
- Aldose Reductase Regulates Doxorubicin-Induced Immune and Inflammatory Responses by Activating Mitochondrial Biogenesis
- Authors: Sonowal, H., Saxena, A., Qiu, S., Srivastava, S., Ramana, K.V.
- Year: 2021
- Citations: 13
- Development of Aldose Reductase Inhibitors for the Treatment of Inflammatory Disorders and Cancer: Current Drug Design Strategies and Future Directions
- Authors: Sonowal, H., Ramana, K.V.
- Year: 2021
- Citations: 17
- 2′-Hydroxyflavanone Prevents LPS-Induced Inflammatory Response and Cytotoxicity in Murine Macrophages
- Authors: Sonowal, H., Ramana, K.V.
- Year: 2020
- Citations: 8
- Didymin by Suppressing NF-κB Activation Prevents VEGF-Induced Angiogenesis in Vitro and In Vivo
- Authors: Shukla, K., Sonowal, H., Saxena, A., Ramana, K.V.
- Year: 2019
- Citations: 20
- Erratum: Expression of Concern: Aldose Reductase Mediates the Lipopolysaccharide-Induced Release of Inflammatory Mediators in RAW264.7 Murine Macrophages
- Authors: Ramana, K.V., Fadl, A.A., Tammali, R., Chopra, A.K., Srivastava, S.K.
- Year: 2019
- Citations: 0
