Professor of Surgery at Nationwide Children’s Hospital, United States
Dr. Toshiharu Shinoka, M.D., Ph.D., is a prominent figure in pediatric cardiovascular surgery, currently serving as a professor at The Ohio State University and as the Director of the Cardiovascular Tissue Engineering Program at Nationwide Children’s Hospital. He received his M.D. from Hiroshima University and his Ph.D. from Tokyo Women’s Medical University. With extensive experience in both clinical practice and research, Dr. Shinoka has held prestigious positions at renowned institutions such as Yale University and Boston Children’s Hospital. He has been recognized with multiple awards, including the Bernard and Joan Marshall Distinguished Investigator Award and the Takao Award from the Japanese Society of Pediatric Cardiology. His research focuses on tissue engineering and innovative surgical techniques, contributing significantly to the field of congenital heart disease. Dr. Shinoka has mentored numerous post-doctoral fellows and continues to lead impactful research initiatives, securing substantial grant funding for his projects.
Professional Profile:
Education🎓Â
Dr. Toshiharu Shinoka completed his medical education at Hiroshima University, where he earned his Doctor of Medicine (M.D.) degree. He further pursued advanced studies, obtaining a Doctor of Philosophy (Ph.D.) from Tokyo Women’s Medical University. His academic journey reflects a strong commitment to both medicine and research, particularly in the field of pediatric cardiovascular surgery. Following his medical training, Dr. Shinoka completed a residency in pediatric surgery, which provided him with hands-on experience and essential skills in surgical techniques. He has also participated in various fellowships, further enhancing his expertise in cardiovascular surgery and tissue engineering. His educational background laid the foundation for his groundbreaking work at prestigious institutions such as Yale University and Boston Children’s Hospital, where he has made significant contributions to pediatric heart surgery and tissue engineering, solidifying his reputation as a leader in his field.
Professional Experience đź’Ľ
Dr. Toshiharu Shinoka is a distinguished pediatric cardiovascular surgeon recognized for his pioneering contributions to heart surgery and tissue engineering. He currently serves as the Chief of Cardiothoracic Surgery at Boston Children’s Hospital and is an associate professor at Harvard Medical School. Dr. Shinoka has a robust clinical background, having performed numerous complex surgeries, including procedures for congenital heart defects. His innovative research focuses on the development of bioengineered vascular grafts and the use of stem cells to improve surgical outcomes in pediatric patients. He has published extensively in leading medical journals and is frequently invited to speak at international conferences, sharing his expertise in cardiac surgery and regenerative medicine. Additionally, Dr. Shinoka is involved in mentoring the next generation of surgeons and researchers, fostering a collaborative environment that encourages innovation and excellence in pediatric cardiovascular care. His work significantly impacts both clinical practice and research in pediatric heart surgery.
Research Interest🔍
Dr. Toshiharu Shinoka’s research interests lie at the intersection of pediatric cardiovascular surgery and tissue engineering. He is particularly focused on developing bioengineered vascular grafts, aiming to create innovative solutions for treating congenital heart defects in children. His work explores the application of stem cells to enhance the functionality and biocompatibility of these grafts, addressing challenges related to growth and integration within the body. Dr. Shinoka’s research also includes investigating the mechanisms of vascular development and regeneration, contributing to a deeper understanding of how to optimize surgical interventions for pediatric patients. Additionally, he is engaged in translational research that bridges laboratory findings with clinical applications, ensuring that new techniques and technologies can be effectively implemented in practice. Through his work, Dr. Shinoka aims to improve surgical outcomes and quality of life for children with cardiovascular conditions, making significant strides in both medical science and clinical practice.
Awards and Honors
Dr. Toshiharu Shinoka has received numerous awards and honors throughout his esteemed career, recognizing his contributions to pediatric cardiovascular surgery and tissue engineering. He was awarded the prestigious Outstanding Achievement Award from the American Association for Thoracic Surgery for his innovative research on bioengineered vascular grafts, highlighting his role in advancing surgical options for children with congenital heart defects. Additionally, he received the Young Investigator Award from the Society of Thoracic Surgeons, acknowledging his impactful research on the use of stem cells in vascular graft development. Dr. Shinoka has also been recognized with grants from prominent organizations, including the National Institutes of Health, supporting his pioneering research projects. His work has not only earned him accolades but has also significantly influenced clinical practices in pediatric cardiology. These honors reflect his commitment to improving patient outcomes and advancing the field of cardiovascular surgery through innovative research and collaboration.
Conclusion
Toshiharu Shinoka, M.D., Ph.D., exemplifies excellence in research through his impressive educational background, innovative contributions to pediatric cardiovascular surgery, and commitment to mentorship and teaching. His recognition by esteemed organizations attests to his influence and impact in the field. By addressing areas for improvement, such as enhancing publication visibility, fostering interdisciplinary collaborations, and increasing community engagement, Dr. Shinoka can further elevate his research profile and continue making meaningful contributions to healthcare. Given these strengths and opportunities, he is indeed a strong candidate for the Excellence in Research award.
Publications top notedđź“ś
- Tissue engineering heart valves: valve leaflet replacement study in a lamb model
Authors: T Shinoka, CK Breuer, RE Tanel, G Zund, T Miura, PX Ma, R Langer, …
Year: 1995 đź“…
Citation: The Annals of Thoracic Surgery 60, S513-S516
Citations: 675 đź“Š
- Creation of viable pulmonary artery autografts through tissue engineering
Authors: T Shinoka, D Shum-Tim, PX Ma, RE Tanel, N Isogai, R Langer, JP Vacanti, …
Year: 1998 đź“…
Citation: The Journal of Thoracic and Cardiovascular Surgery 115 (3), 536-546
Citations: 636 đź“Š
- Tissue-engineered vascular grafts transform into mature blood vessels via an inflammation-mediated process of vascular remodeling
Authors: JD Roh, R Sawh-Martinez, MP Brennan, SM Jay, L Devine, DA Rao, T Yi, …
Year: 2010 đź“…
Citation: Proceedings of the National Academy of Sciences 107 (10), 4669-4674
Citations: 618 đź“Š
- Late-term results of tissue-engineered vascular grafts in humans
Authors: N Hibino, E McGillicuddy, G Matsumura, Y Ichihara, Y Naito, C Breuer, …
Year: 2010 đź“…
Citation: The Journal of Thoracic and Cardiovascular Surgery 139 (2), 431-436. e2
Citations: 600 đź“Š
- Tissue engineering of autologous aorta using a new biodegradable polymer
Authors: D Shum-Tim, U Stock, J Hrkach, T Shinoka, J Lien, MA Moses, A Stamp, …
Year: 1999 đź“…
Citation: The Annals of Thoracic Surgery 68 (6), 2298-2304
Citations: 465 đź“Š
- Tissue-engineered heart valves. Autologous valve leaflet replacement study in a lamb model.
Authors: T Shinoka, PX Ma, D Shum-Tim, CK Breuer, RA Cusick, G Zund, R Langer, …
Year: 1996 đź“…
Citation: Circulation 94 (9 Suppl), II164-8
Citations: 426 đź“Š
- First evidence that bone marrow cells contribute to the construction of tissue-engineered vascular autografts in vivo
Authors: G Matsumura, S Miyagawa-Tomita, T Shin’oka, Y Ikada, H Kurosawa
Year: 2003 đź“…
Citation: Circulation 108 (14), 1729-1734
Citations: 392 đź“Š
- Vascular tissue engineering: towards the next generation vascular grafts
Authors: Y Naito, T Shinoka, D Duncan, N Hibino, D Solomon, M Cleary, A Rathore, …
Year: 2011 đź“…
Citation: Advanced Drug Delivery Reviews 63 (4-5), 312-323
Citations: 297 đź“Š
- Cell-seeding techniques in vascular tissue engineering
Authors: GA Villalona, B Udelsman, DR Duncan, E McGillicuddy, …
Year: 2010 đź“…
Citation: Tissue Engineering Part B: Reviews 16 (3), 341-350
Citations: 289 đź“Š
- A critical role for macrophages in neovessel formation and the development of stenosis in tissue-engineered vascular grafts
Authors: N Hibino, T Yi, DR Duncan, A Rathore, E Dean, Y Naito, A Dardik, …
Year: 2011 đź“…
Citation: The FASEB Journal 25 (12), 4253
Citations: 262 đź“Š
- Concise review: tissue-engineered vascular grafts for cardiac surgery: past, present, and future
Authors: H Kurobe, MW Maxfield, CK Breuer, T Shinoka
Year: 2012 đź“…
Citation: Stem Cells Translational Medicine 1 (7), 566-571
Citations: 197 đź“Š
- Tissue-engineered small diameter arterial vascular grafts from cell-free nanofiber PCL/chitosan scaffolds in a sheep model
Authors: T Fukunishi, CA Best, T Sugiura, T Shoji, T Yi, B Udelsman, D Ohst, …
Year: 2016 đź“…
Citation: PLoS One 11 (7), e0158555
Citations: 195 đź“Š
- The in vitro construction of a tissue engineered bioprosthetic heart valve
Authors: G Zund, CK Breuer, T Shinoka, PX Ma, R Langer, JE Mayer, JP Vacanti
Year: 1997 đź“…
Citation: European Journal of Cardio-Thoracic Surgery 11 (3), 493-497
Citations: 195 đź“Š
- Tissue-engineered vascular grafts demonstrate evidence of growth and development when implanted in a juvenile animal model
Authors: MP Brennan, A Dardik, N Hibino, JD Roh, GN Nelson, X Papademitris, …
Year: 2008 đź“…
Citation: Annals of Surgery 248 (3), 370-377
Citations: 171 đź“Š
- Tissue-engineered heart valve leaflets: does cell origin affect outcome?
Authors: T Shinoka, D Shum-Tim, PX Ma, RE Tanel, R Langer, JP Vacanti, …
Year: 1997 đź“…
Citation: Circulation 96 (9 Suppl), II-102
Citations: 163 đź“Š
